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Open AccessJournal ArticleDOI

Rapid dereplication of microbial isolates using matrix-assisted laser desorption ionization time-of-flight mass spectrometry: A mini-review.

Doreen Huschek, +1 more
- 02 Apr 2019 - 
- Vol. 19, pp 99-104
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TLDR
In this paper, a review of the use of matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for the classification and characterization of plant-associated microorganisms is presented.
About
This article is published in Journal of Advanced Research.The article was published on 2019-04-02 and is currently open access. It has received 18 citations till now. The article focuses on the topics: Mass spectrometry.

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Citations
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The Gibberellin Producer Fusarium fujikuroi: Methods and Technologies in the Current Toolkit

TL;DR: The currently available research tools/methods for F. fujikuroi research are reviewed, focusing on the topics about genetic engineering and gibberellin production.
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A Comparative Analysis of Ash Leaf-Colonizing Bacterial Communities Identifies Putative Antagonists of Hymenoscyphus fraxineus.

TL;DR: This study studies compound leaves from susceptible and visible infection-free trees in four ash stands with a high likelihood of infection to assess a possible variation in the bacterial microbiota, depending on the health status of the trees, and provides a set of isolates or phylogenetic groups that might be involved in the process that prevents the penetration and spread of H. fraxineus.
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Analyzing Ash Leaf-Colonizing Fungal Communities for Their Biological Control of Hymenoscyphus fraxineus.

TL;DR: The invasive ascomycete Hymenoscyphus fraxineus has been threatening Fraxinus excelsior populations throughout Europe for over two decades and leaf-colonizing microorganisms have been discussed as a barrier and as possible biocontrol agents against the disease.
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Capillary electrophoresis as a powerful tool for the analyses of bacterial samples

TL;DR: Recent applications of electrokinetic methods in combination with various detection systems and on-line concentration techniques for the analysis of bacterial metabolites, cell components, and bacteria are reviewed.
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Artificial intelligence-guided discovery of anticancer lead compounds from plants and associated microorganisms

TL;DR: An overview of current AI-guided solutions to discover anticancer lead compounds, focusing on natural products from plants and associated microorganisms, can be found in this paper, where the authors present an overview of the current state-of-the-art.
References
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Journal ArticleDOI

MALDI-TOF mass spectrometry: an emerging technology for microbial identification and diagnosis.

TL;DR: An overview of the status and recent applications of mass spectrometry for microbial identification is provided and the usefulness of this exciting new technology for diagnosis of diseases caused by bacteria, viruses, and fungi is explored.
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Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry: a Fundamental Shift in the Routine Practice of Clinical Microbiology

TL;DR: This review summarizes the current position of MALDI-TOF MS in clinical research and in diagnostic clinical microbiology laboratories and serves as a primer to examine the “nuts and bolts” of MalDI-toF MS, highlighting research associated with sample preparation, spectral analysis, and accuracy.
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Rapid Identification of Intact Whole Bacteria Based on Spectral Patterns using Matrix‐assisted Laser Desorption/Ionization with Time‐of‐flight Mass Spectrometry

TL;DR: This work represents the first reported instance of successful bacterial chemotaxonomy by MALDI-TOFMS analysis of whole cells, and shows a few characteristic high-mass ions which are thought to be derived from bacterial proteins.
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The rapid identification of intact microorganisms using mass spectrometry

TL;DR: The application of MALDI-TOF-MS is reported for the identification of intact Gram-negative and Gram-positive microorganisms taken directly from culture, providing a unique mass spectral fingerprint of the microorganism, produced from desorbed components of the cell wall.
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The Rebirth of Culture in Microbiology through the Example of Culturomics To Study Human Gut Microbiota

TL;DR: It is demonstrated that both empirical and hypothesis-driven approaches will enable a rapid increase in the identification of the human prokaryote repertoire, and taxonogenomics strategies became an emerging method for describing new species.
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