Rat Ovarian 20±-Hydroxysteroid Dehydrogenase-1 May Belong to Aldo-Keto Reductase Superfamily
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This article is published in Journal of Reproduction and Development.The article was published on 1993-01-01 and is currently open access. It has received 1 citations till now. The article focuses on the topics: Hydroxysteroid dehydrogenase & Aldo-keto reductase.read more
Citations
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Journal ArticleDOI
Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.
Maho Ishida,Jae Hyek Choi,Keiji Hirabayashi,Takashi Matsuwaki,Masatoshi Suzuki,Masatoshi Suzuki,Keitaro Yamanouchi,Reiko Horai,Katsuko Sudo,Yoichiro Iwakura,Masugi Nishihara +10 more
TL;DR: The findings suggest that the role of 20alpha-HSD in functional luteolysis is relatively minor but that it is involved in the survival of newborn mice.
References
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Ubiquitin-Mediated Pathways for Intracellular Proteolysis
TL;DR: The presence of Ub on histones and on the lymphocyte homing receptor suggests that ubiquitination does not serve exclusively to mark proteins for degradation, and this abundant protein may serve as an intracellular barometer whose distribution among several pools regulates a variety of processes.
Journal Article
Regulation of T cell differentiation: in vitro induction of 20 alpha-hydroxysteroid dehydrogenase in splenic lymphocytes from athymic mice by a unique lymphokine.
J N Ihle,L Pepersack,L Rebar +2 more
TL;DR: In vivo, the expression of 20 alpha SDH is thymus dependent, in that splenic lymphocytes from athymic mice have only low levels of activity, although the levels of enzyme activity increase gradually with age, and induction is blocked by mitomycin C, suggesting a requirement for cell proliferation.
Book ChapterDOI
Limited N-terminal sequence analysis.
TL;DR: Current methods in protein purification permit sequence analysis of picomole quantities of proteins and peptides, but the key to obtaining sequence is to choose as the last step in the purification protocol the simplest method for isolating the protein or peptide.
Journal ArticleDOI
Cytoplasmic aldo-keto reductases: a class of drug metabolizing enzymes
TL;DR: These reductases define a system of detoxification for aldehyde and ketone groups and require reduced nicotinamide adenine dinucleotide as cofactor for the reductions.
Journal ArticleDOI
Cloning and sequencing of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.
TL;DR: The sequence data presented suggests that 3 alpha-HSD, prostaglandin F synthase, and aldehyde/aldose reductases are members of a common gene family.