Journal ArticleDOI
Recognition of partial defects in antidiuretic hormone secretion.
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A dehydration procedure has been used to identify patients with partial antidiuretic hormone (ADH) deficiency and the test consists of water deprivation until the osmolality of hourly voided urine is voided.Abstract:
A dehydration procedure has been used to identify patients with partial antidiuretic hormone (ADH) deficiency. The test consists of water deprivation until the osmolality of hourly voided ...read more
Citations
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Journal ArticleDOI
Hypothalamic dysfunction in secondary amenorrhea associated with simple weight loss.
TL;DR: It is concluded that hypothalamic dysfunction may be caused by weight loss per se and not related to anorexia nervosa.
Journal ArticleDOI
On the mechanism of lithium-induced diabetes insipidus in man and the rat.
TL;DR: The present studies suggest that nephrogenic diabetes insipidus is a common finding after lithium treatment and results in part from interference with the mediation of vasopressin at a step distal to the formation of 3',5' cyclic AMP.
Journal ArticleDOI
The clinical and endocrine outcome to trans-sphenoidal microsurgery of nonsecreting pituitary adenomas
TL;DR: Data indicate that trans‐sphenoidal microsurgery is an effective and safe initial treatment for patients with nonsecreting pituitary adenoma and may reverse hypopituitarism.
Journal ArticleDOI
Mineralocorticoid-resistant renal hyperkalemia without salt wasting (type II pseudohypoaldosteronism): role of increased renal chloride reabsorption.
TL;DR: It is suggested that the primary abnormality in this syndrome increases the reabsorptive avidity of the distal nephron for chloride, which limits the sodium and mineralocorticoid-dependent voltage driving force for potassium and hydrogen ion secretion, resulting in hyperkalemia and acidosis and augments distal sodium chloride reabsorption resulting inhyperchloremia, volume expansion, hyporeninemia, and hypertension.
Journal ArticleDOI
A comparison of plasma vasopressin measurements with a standard indirect test in the differential diagnosis of polyuria.
TL;DR: It is concluded that the incorporation of a vasopressin assay improves accuracy in the differential diagnosis of polyuria and may be explained by increased sensitivity to low concentrations of vasoppressin in the former disorder and a reduction of maximal concentrating ability in both.
References
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Journal ArticleDOI
The effect of a high water intake on the kidney's ability to concentrate the urine in man.
H. E. de Wardener,A. Herxheimer +1 more
Journal ArticleDOI
The use of hypertonic saline infusions in the differential diagnosis of diabetes insipidus and psychogenic polydipsia.
Anne C. Carter,Jacob Robbins +1 more
TL;DR: Hare and his associates in a series of studies on normal dogs have shown that the concentration of chlorides in the tubular reabsorbate (R), the ratio of R to plasma chlorides (R/P) and the urine flow, are all decreased following infusions of hypertonic saline, concomitantly with an increase of antidiuretic substance in the urine.
Journal ArticleDOI
The renal excretion of chloride and water in diabetes insipidus.
Robert C. Hickey,Kendrick Hare +1 more
Journal ArticleDOI
A water deprivation test for the differential diagnosis of polyuria.
TL;DR: A relatively simple, standardized 6 1/2 hour water deprivation test is described which adequately differentiates disorders of the neurohypophyseal-hypothalamic system from primary polydipsia and patients with diabetes insipidus demonstrate defective urinary concentrating capacity.