Journal ArticleDOI
Red cell surface structure: Stabilization by cholesterol sulfate as evidenced by scanning electron microscopy
TLDR
Scanning electron microscopic studies demonstrate that the normal biconcave shape of the human erythrocyte is maintained in hypotonic saline when physiological levels (10 minus 5M) of cholesterol sulfate are added to the solutions.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1975-01-28. It has received 43 citations till now. The article focuses on the topics: Sterol & Membrane.read more
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Ordering effects of cholesterol and its analogues
Tomasz Róg,Marta Pasenkiewicz-Gierula,Ilpo Vattulainen,Ilpo Vattulainen,Ilpo Vattulainen,Mikko Karttunen +5 more
TL;DR: The biophysical effects of cholesterol on the lipid bilayer are discussed, in particular the ordering and condensing effects, concentrating on the molecular level or inter-atomic interactions perspective, starting from two-component systems and proceeding to many-component ones e.g., modeling lipid rafts.
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A molecular membrane model of sperm capacitation and the acrosome reaction of mammalian spermatozoa
TL;DR: The model illustrates enzymatic reactions which are believed to regulate the permeability and integrity of the plasma membrane overlying the acrosome during interactions between the male gamete and capacitation factors present in fluids of the female genital tract.
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Cholesterol sulfate in human physiology: what's it all about?
Charles A. Strott,Yuko Higashi +1 more
TL;DR: The accumulating evidence demonstrating a regulatory function for cholesterol sulfate appears solid; the challenge now is to work out the molecular mechanisms whereby this interesting molecule carries out its various roles.
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Changes in the lipid content of boar sperm plasma membranes during epididymal maturation
TL;DR: Plasma membranes of boar sperm from caput, corpus and cauda of the epididymis were purified by differential- and sucrose-density equilibrium centrifugation and were found to yield a single band at a density of 1.13 g/cm3, which may help to explain the decreased resistance to cold shock and changes in membrane fluidity of sperm during transit in the epidIDymis.
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The ichthyoses--pathogenesis and prenatal diagnosis: a review of recent advances.
TL;DR: The evidence linking the various ichthyoses to defects in protein or lipid metabolism have been reviewed and it is likely that future advances will lead not only to a more complete understanding of the pathogenesis of these disorders, but also will shed significant light on the normal stratum corneum functions of barrier formation and desquamation and lead the way to more rational and effective therapies.
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The assay of cholesterol sulfate in biological material by enzymatic radioisotopic displacement.
TL;DR: A technique is described which is based upon the displacement of labelled CS from a placental sulfatase enzyme system by the addition of unlabelled CS isolated from various biological sources and provides values which are in good agreement with those obtained by a double isotope derivative assay.
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Are inorganic cations essential for the stability of biological membranes
TL;DR: In this system, it is possible to remove protein components from the major portion of the lipid without drastically altering their conformation and without the use of organic solvents or detergents to solubilize the lipid, and it is now possible to fractionate these proteins, study their properties, and define the nature of their interactions with various types of lipid normally present in the intact membrane.
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Cholesterol Sulfate: Some Aspects of Its Biosynthesis and Uptake by Tissues from Blood
TL;DR: The ability of a variety of tissues of the guinea pig to synthesize cholesterol sulfate from 35SO4= has been measured whereas, surprisingly, synthesis of the conjugate in steroid-producing endocrine organs (adrenals, testes and ovaries) was barely detectable.