Journal ArticleDOI
Regional differences in the regulation of dopamine and noradrenaline release in medial frontal cortex, nucleus accumbens and caudate-putamen: a microdialysis study in the rat.
TLDR
The results show that the forebrain DA and NA projections to cortical and striatal targets are differentially regulated during ongoing behavior, that the mesocortical and mesostriatal DA systems respond quite differently to stressful and rewarding stimuli; and that the NA projection to MFC is more responsive to stressfuland rewarding stimuli than the ones innervating the striatum.About:
This article is published in Brain Research.The article was published on 1992-05-29. It has received 241 citations till now. The article focuses on the topics: Striatum & Nucleus accumbens.read more
Citations
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A neuropsychological theory of positive affect and its influence on cognition.
TL;DR: A new neuropsychological theory is proposed that accounts for many of the effects of positive affect on olfaction, the consolidation of long-term memories, working memory, and creative problem solving by assuming that positive affect is associated with increased brain dopamine levels.
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The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking
Satoshi Ikemoto,Jaak Panksepp +1 more
TL;DR: The present analysis suggests that NAS DA plays an important role in sensorimotor integrations that facilitate flexible approach responses, and offers the following interpretation for the finding that both conditioned and unconditioned aversive stimuli stimulate DA release in the NAS: NAS DA invigorates approach responses toward 'safety'.
Journal ArticleDOI
Mesolimbocortical and nigrostriatal dopamine responses to salient non-reward events.
TL;DR: Evidence showing that dopamine neurons respond to salient and arousing change in environmental conditions, regardless of the motivational valence of that change is examined, and how this might shape the thinking about the role of dopamine systems in goal-directed behavior is asked.
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The involvement of nucleus accumbens dopamine in appetitive and aversive motivation
TL;DR: It is suggested that nucleus accumbens dopamine is involved in aspects of sensorimotor functions that are involved in both appetitive and aversive motivation.
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Dopamine Axon Varicosities in the Prelimbic Division of the Rat Prefrontal Cortex Exhibit Sparse Immunoreactivity for the Dopamine Transporter
TL;DR: In this article, the authors investigated whether the greater diffusion of dopamine in the rat prefrontal cortex (PFC) as compared with the striatum is associated with a more restricted axonal distribution of the cortical DAT protein.
References
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Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine.
TL;DR: Modification of the original single isotope radioenzymatic assay of Passon and Peuler permits the direct and simultaneous analysis of norepinephrine, epinephrine and dopamine in plasma samples of 50 μl or less.
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Nucleus locus ceruleus: new evidence of anatomical and physiological specificity
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Mesocorticolimbic dopaminergic network: functional and regulatory roles
M. Le Moal,H. Simon +1 more
TL;DR: Article de synthese sur le reseau dopaminergique mesocorticolimbique chez les mammiferes dans le cerveau en fonction du comportement and en f onction de l'individu.
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Differential Effect of Stress on In Vivo Dopamine Release in Striatum, Nucleus Accumbens, and Medial Frontal Cortex
TL;DR: Microdialysis was used to assess extracellular dopamine in striatum, nucleus accumbens, and medial frontal cortex of unanesthetized rats both under resting conditions and in response to intermittent tail‐shock stress, providing direct in vivo evidence for the global activation of dopaminergic systems by stress.
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Selective activation of mesocortical DA system by stress.
TL;DR: The results suggest that the mesocortical DA system is selectively activated by this stress induced by electric foot shocks, and the antipsychotic effects of neuroleptics are in part related to the blockade of postsynaptic DA receptors localised in areas innervated by the mesolimbic and mesocORTical DA systems.