Journal ArticleDOI
Regulation and cell autonomy during postembryonic development of Caenorhabditis elegans
John Sulston,John G. White +1 more
TLDR
The role of cell-cell interaction in the postembryonic development of nongonadal tissues in the nematode Caenorhabditis elegans has been explored by selective cell ablation with a laser microbeam and examples have been found of induction and of regulation in cell lineage and fate.About:
This article is published in Developmental Biology.The article was published on 1980-08-01. It has received 514 citations till now. The article focuses on the topics: Caenorhabditis elegans.read more
Citations
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The roles of EGF and Wnt signaling during patterning of the C. elegans Bγ/δ Equivalence Group
Adeline Seah,Paul W. Sternberg +1 more
TL;DR: ceh-13/labial/Hox1 expression in Bγ is regulated by the EGF pathway and downstream factors lin-1/ETS lin-31/Forkhead and sur-2/MED23, and Wnt signaling is required for proper Bγ division, perhaps to orient the Bγ mitotic spindle.
Journal ArticleDOI
A phylogenetic interpretation of nematode vulval variations
Ralf J. Sommer,Carola B. Sigrist,Kaj Grandien,Benno Jungblut,Andreas Eizinger,Helena Adamis,Isabel Schlak +6 more
TL;DR: The comparative data of vulva development is placed onto this phylogeny of nematodes to infer the direction of evolutionary change.
Journal ArticleDOI
Cell lineage in development.
TL;DR: These findings suggested that the differentiated properties which characterize a given cell of the mature animal are causally linked with that cell’s developmental line of descent.
References
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Journal ArticleDOI
The genetics of caenorhabditis elegans
TL;DR: In this paper, the authors describe methods for the isolation, complementation and mapping of mutants of Caenorhabditis elegans, a small free-living nematode worm.
Journal ArticleDOI
Post-embryonic cell lineages of the nematode, Caenorhabditis elegans
John Sulston,H.R. Horvitz +1 more
TL;DR: These cell lineages range in length from one to eight sequential divisions and lead to significant developmental changes in the neuronal, muscular, hypodermal, and digestive systems and are determined by direct observation of the divisions, migrations, and deaths of individual cells in living nematodes.
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The postembryonic cell lineages of the hermaphrodite and male gonads in Caenorhabditis elegans
Judith Kimble,David Hirsh +1 more
TL;DR: Variation in the hermaphrodite lineage suggests that cell-cell interaction may play a more significant role in organisms that develop by invariant lineages than has hitherto been considered.
Journal ArticleDOI
The structure of the ventral nerve cord of Caenorhabditis elegans
TL;DR: The nervous system of Caenorhabditis elegans is arranged as a series of fibre bundles which run along internal hypodermal ridges and three of the motor neurone classes receive their synaptic input from a set of interneurones coming from the nerve ring.