Journal ArticleDOI
Renal failure in the patient with cirrhosis: The role of active vasoconstriction
Murray Epstein,Dennis P. Berk,Norman K. Hollenberg,Douglass F. Adams,Thomas C. Chalmers,Herbert L. Abrams,John P. Merrill +6 more
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TLDR
The arteriographic findings, including the absence of a cortical nephrogram and unrecognizable renal cortical vasculature in the patients with the most severe degree of renal failure, support the concept of a reduction in renal cortical perfusion.About:
This article is published in The American Journal of Medicine.The article was published on 1970-08-01. It has received 416 citations till now. The article focuses on the topics: Renal blood flow & Renal artery.read more
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Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis
Vicente Arroyo,Pere Ginès,Alexander L. Gerbes,F J Dudley,Paolo Gentilini,Giacomo Laffi,Telfer B. Reynolds,H. Ring-Larsen,J Schölmerich +8 more
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Incidence, predictive factors, and prognosis of the hepatorenal syndrome in cirrhosis with ascites
Angels Ginès,Angels Escorsell,Pere Ginès,Joan Saló,Wladimiro Jiménez,Luis Inglada,Miquel Navasa,Joan Clària,Antoni Rimola,Vicente Arroyo,Joan Rodés +10 more
TL;DR: The hepatorenal syndrome is a relatively frequent complication in cirrhotic patients with ascites that is associated with an extremely short survival and Liver size, plasma renin activity, and serum sodium concentration are predictors of hepatorenAL syndrome occurrence in these patients.
Journal ArticleDOI
Management of cirrhosis and ascites.
TL;DR: The authors describe measures for the control of ascites as well as strategies for its management and for the prevention of major complications, including gastrointestinal bleeding, spontaneous bacterial peritonitis, and the hepatorenal syndrome.
Journal ArticleDOI
False neurotransmitters and hepatic failure.
Fischer Je,Ross J. Baldessarini +1 more
TL;DR: This hypothesis is consistent with many clinical and biochemical observations about hepatic failure, hepatic coma, and the "hepatorenal syndrome" and may explain the beneficial effects of L-dopa on the mental and circulatory status of patients in hepatic Failure and the satisfactory treatment of the hepatorenal Syndrome with large doses of metaraminol or other α-adrenergic amines.
Journal ArticleDOI
Acute kidney injury in cirrhosis
TL;DR: Specific therapies of AKI depend on the most likely cause and mechanism, and Vasoconstrictors are useful bridging therapies in HRS.
References
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On the colorimetric determination of creatinine by the jaffe reaction
Roy W. Bonsnes,Hertha H. Taussky +1 more
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Regional Blood Flow of the Cerebral Cortex Determined by Krypton85
David H. Ingvar,Niels A. Lassen +1 more
TL;DR: A new method for determining regional blood flow by means of the lnert radloactlve gas Krypton/sup 85/ presented and to confirm and to study in quantltative terms the correlation between arterial; carbon dloxlde tenslon or cortical functional actlvity, and the reglonaI cortlcal blood flow is presented.
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Acute oliguric renal failure in man: evidence for preferential renal cortical ischemia.
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Intrarenal Distribution of Nutrient Blood Flow Determined with Krypton85 in the Unanesthetized Dog
Geoffrey D. Thorburn,Hugh H. Kopald,J. Alan Herd,Milton Hollenberg,Charles C. C. O'morchoe,A. Clifford Barger +5 more
TL;DR: A method has been described for the measurement, by means of Kr85, of intrarenal nutrient blood flow distribution in the unanesthetized dog and the importance of these findings has been discussed with reference to the anatomy of the kidney.
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Transplantation of cadaveric kidneys from patients with hepatorenal syndrome. Evidence for the functionalnature of renal failure in advanced liver disease.
Marcelo H. Koppel,Jack W. Coburn,Matlock M. Mims,Howard Goldstein,James D. Boyle,Milton E. Rubini +5 more
TL;DR: A kidney from each of five patients and both kidneys from a sixth patient dying with the hepatorenal syndrome were transplanted into seven patients with end-stage kidney disease whose liver function was normal, and four transplanted kidneys achieved stable function for six months or longer.