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Research of Panax spp. in Kunming Institute of Botany, CAS.

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TLDR
The research progress on Panax spp.
Abstract
Panax, a genus of the Araliaceae family, is an important herbal group in traditional Chinese medicine (TCM) Nine species and three varieties are included in the genus of Panax, in which nearly all species have been used for medicinal purposes Among them, Panax notoginseng (Burk) F H Chen, Panax ginseng C A Meyer and Panax quinquefolius L are the most representative and valuable herbs world-wide, with a long history of cultivation As the main bioactive chemical constituents, saponins with different aglycones are the major components in various Panax spp, and their pharmacological activities are mainly reflected in the effects on blood system, cardio- and cerebro-vascular systems, nervous system, metabolism, and immune regulation Researchers of Kunming Institute of Botany (KIB), Chinese Academy of Sciences (CAS), have put many efforts into conducting the investigations on Panax species Herein, we reviewed the research progress on Panax spp in KIB, CAS, over the past few decades, from the aspects of history and origin, phytochemistry and pharmacological activities

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Application of Identification and Evaluation Techniques for Ethnobotanical Medicinal Plant of Genus Panax: A Review.

TL;DR: The purpose was to review and summarize the species classification, geographical distribution, and ethnic minorities medicinal records of the genus Panax, and further to review the analytical tools and data analysis methods for the authentication and quality assessment of Panax medicinal materials and Chinese patent medicines.
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Therapeutic Effects of Ten Commonly Used Chinese Herbs and Their Bioactive Compounds on Cancers.

TL;DR: Ten commonly used Chinese herbs that have, for centuries, shown effectiveness in treating cancers are examined, showing the abilities to promote the apoptosis of cancer cells, inhibit their metastasis, activate the patient's anticancer immunity, and synergistically increase the efficacy of conventional chemotherapy and radiation therapy when used in combination.
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Effect of Panax notoginseng Saponins and Major Anti-Obesity Components on Weight Loss.

TL;DR: In this paper, the anti-obesity potential and mechanism of action of notoginsenosides were analyzed; thus laying emphasis on the timely prevention and treatment of obesity, which is necessary to find more effective and safer antiobesity drugs.
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A β‐1,3‐glucanase gene from Panax notoginseng confers resistance in tobacco to Fusarium solani

TL;DR: It is indicated that the PnGlu1 is a vital defense gene during response to F. solani.
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Allelochemicals of Panax notoginseng and their effects on various plants and rhizosphere microorganisms

TL;DR: Results suggest that these isolated ursane-type triterpenoid acids and anthraquinone are potential allelochemicals that contribute to continuous-cropping obstacles of P. notoginseng.
References
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Journal ArticleDOI

Traditional uses, botany, phytochemistry, pharmacology and toxicology of Panax notoginseng (Burk.) F.H. Chen: A review.

TL;DR: The botany, ethnopharmacology, phytochemistry, pharmacology and toxicology of P. notoginseng is summarized comprehensively for the first time and the plant has pharmacological effects on the cardiovascular system, immune system as well as anti-inflammatory, anti-atherosclerotic, haemostatic and anti-tumour activities.
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Saponins of Panax notoginseng: chemistry, cellular targets and therapeutic opportunities in cardiovascular diseases

TL;DR: This review summarizes and critically appraise the latest literature, which study PNS as potential therapeutic agents against CVDs, and introduces the structures of major PNS types, analyze their cellular targets and associated signaling pathways and discuss the emerging opportunities for their clinical applications.
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Misdiagnosis and undiagnosis due to pattern similarity in Chinese medicine: a stochastic simulation study using pattern differentiation algorithm

TL;DR: Applied in an incremental manner, Four Examinations progressively reduce the association between pattern similarity and pattern differentiation outcome and are recommended to avoid misdiagnosis and undiagnosis due to similarity.
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Complete assignment of 1H and 13C NMR data for nine protopanaxatriol glycosides

TL;DR: Nine protopanaxatriol glycosides isolated from mild acid hydrolysis products of crude root saponins of Panax notoginseng were identified, including ginsenoside‐Re and ‐Rg2, and complete NMR assignments of the other seven glycoside are reported for the first time.
Journal ArticleDOI

Dammarane Saponins of Leaves And Seeds of Panax Notoginseng

TL;DR: In this article, from the leaves of Panax notoginseng, cultivated in Yunnan, China, four known saponins of (20S)-protopanaxadiol; gypenoside-IX, ginsenosides-Rb1, -Rb3 and -Rc, and three new (notoginsenoside-Fa, -Fc and -Fe) were isolated.