Journal ArticleDOI
Retinal Vessel Oxygen Saturation in Healthy Individuals
Asbjorg Geirsdottir,Olafur Petur Palsson,Sveinn Hakon Hardarson,Olof Birna Olafsdottir,Jona Valgerdur Kristjansdottir,Einar Stefánsson +5 more
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TLDR
Retinal arteriolar oxygen saturation is stable in healthy individuals, while there is a significant decrease in venular oxygen saturation with age in males and a similar trend in females, and AV difference increases significantly with age for both sexes.Abstract:
Prevention of Blindness Fund
Landspitali-University Hospital Research Fund
University of Iceland Research Fund
Icelandic Center for Research (Rannis) Fundread more
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Retinal oxygen: from animals to humans
Robert A. Linsenmeier,Hao Zhang +1 more
TL;DR: Measurements made with two of the principal methods used to study O2 in the retina are discussed, focusing on measurements of PO2 with oxygen-sensitive microelectrodes in vivo in animals with a retinal circulation similar to that of humans, and oximetry, which can be used non-invasively in both animals and humans to measure O2 concentration in retinal vessels.
Journal ArticleDOI
The oxygen saturation in retinal vessels from diabetic patients depends on the severity and type of vision‐threatening retinopathy
TL;DR: Using retinal oximetry, it has been shown that the oxygen saturation is increased in retinal arterioles and venules from diabetic patients with Retinopathy, but oxygenation before the development of retinopathy and possible differences inretinal oxygenation between diabetic maculopathy and proliferative diabetic retinopathic patients have not been evaluated.
Journal ArticleDOI
Ocular blood flow in glaucoma - the Leuven Eye Study.
Luís Abegão Pinto,Koen Willekens,Karel Van Keer,Abraham Shibesh,Geert Molenberghs,Geert Molenberghs,Evelien Vandewalle,Ingeborg Stalmans +7 more
TL;DR: This study would likely help to identify which of these vascular data can be used as a clinical tool for screening and disease stratification in patients with elevated intra‐ocular pressure.
Journal ArticleDOI
Oximetry in glaucoma: correlation of metabolic change with structural and functional damage.
Evelien Vandewalle,L. Abegao Pinto,Olof Birna Olafsdottir,Eline De Clerck,Peter Stalmans,Joachim Van Calster,Thierry Zeyen,Einar Stefánsson,Ingeborg Stalmans +8 more
TL;DR: The objective is to determine whether retinal vessel oxygen saturation in patients with glaucoma is associated with structural optic disc and retinal nerve fibre layer changes and visual field defects.
Journal ArticleDOI
Oxygen imaging of living cells and tissues using luminescent molecular probes
TL;DR: Current knowledge regarding the mechanism of phosphorescence quenching of metal complexes by oxygen is described in relation to the oxygen sensitivity of the probes, and recent advances in optical oxygen probes and detection techniques for intracellular and tissue oxygen measurements are reviewed, emphasizing the usefulness of chemical modifications for improving probe properties.
References
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Journal ArticleDOI
Relationships between age, blood pressure, and retinal vessel diameters in an older population.
Harry Leung,Jie Jin Wang,Elena Rochtchina,Ava Grace Tan,Tien Yin Wong,Ronald Klein,Larry D. Hubbard,Paul Mitchell +7 more
TL;DR: Retinal arteriolar and venular diameters narrow with increasing age, and these parameters are inversely related to BP, independent of age, gender, and smoking.
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Snapshot hyperspectral imaging in ophthalmology
TL;DR: A snapshot imaging spectrometer with far-reaching applicability that acquires a complete spatial-spectral image cube in approximately 3 ms from 450 to 700 nm with 50 bands, eliminating motion artifacts and pixel misregistration is presented.
Journal ArticleDOI
Oximetry of retinal vessels by dual-wavelength imaging: calibration and influence of pigmentation
TL;DR: This technique, when combined with blood flow studies in human subjects, will enable the study of retinal O2 utilization under experimental and various disease conditions.
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Automatic retinal oximetry.
Sveinn Hakon Hardarson,Alon Harris,Robert Arnar Karlsson,Gisli H. Halldorsson,Larry Kagemann,Larry Kagemann,Ehud Rechtman,Gunnar Már Zoega,Thor Eysteinsson,Jon Atli Benediktsson,Adalbjorn Thorsteinsson,Peter Koch Jensen,James M. Beach,Einar Stefánsson +13 more
TL;DR: The retinal oximeter is reliable, easy to use, and sensitive to changes in SO(2) when concentration of O(2)'s in inhaled air is changed.
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Noninvasive technique for oximetry of blood in retinal vessels.
TL;DR: Oxygen saturation measurements for blood flowing through glass capillaries are presented as well as representative results of oxygen saturation measurements on normal human subjects.