Journal ArticleDOI
Rhamnolipids form drug-loaded nanoparticles for dermal drug delivery.
Felix Müller,Stefan Hönzke,Wulf-Ole Luthardt,Ee Lin Wong,Michael Unbehauen,Jörg Bauer,Rainer Haag,Sarah Hedtrich,Eckart Rühl,Jörg Rademann +9 more
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TLDR
Rhamnolipid nanocarriers were found to be non‐toxic to primary human fibroblasts in a proliferation assay and thus are considered candidates for the dermal delivery of drugs.About:
This article is published in European Journal of Pharmaceutics and Biopharmaceutics.The article was published on 2017-07-01. It has received 31 citations till now. The article focuses on the topics: Drug carrier & Drug delivery.read more
Citations
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Fabrication and characterization of resveratrol loaded zein-propylene glycol alginate-rhamnolipid composite nanoparticles: Physicochemical stability, formation mechanism and in vitro digestion
Yang Wei,Zhongping Yu,Kangsen Lin,Cuixia Sun,Lei Dai,Shufang Yang,Like Mao,Fang Yuan,Yanxiang Gao +8 more
TL;DR: In this article, resveratrol loaded zein-propylene glycol alginate-rhamnolipid composite nanoparticles were fabricated to overcome the limitations of reserveratrol such as water insolubility and chemical instability.
Journal ArticleDOI
Combination of Rhamnolipid and Chitosan in Nanoparticles Boosts Their Antimicrobial Efficacy
Crisiane Aparecida Marangon,Virginia da Conceição Amaro Martins,Ma H Ling,Cristiane C Melo,Ana Maria de Guzzi Plepis,Rikke Louise Meyer,Marcia Nitschke +6 more
TL;DR: The combination of chitosan and rhamnolipid offers a promising strategy to the design of novel nanoparticles with low cytotoxicity, which can be exploited in pharmaceutical and food industries.
Journal ArticleDOI
Rhamnolipid the Glycolipid Biosurfactant: Emerging trends and promising strategies in the field of biotechnology and biomedicine.
Priyanka Thakur,Neeraj K. Saini,Vijay Kumar Thakur,Vijai Kumar Gupta,Reena V. Saini,Adesh K. Saini +5 more
TL;DR: Rhamnolipids (RLs) are surface-active compounds and belong to the class of glycolipid biosurfactants, mainly produced from Pseudomonas aeruginosa as discussed by the authors.
Journal ArticleDOI
Novel colloidal particles and natural small molecular surfactants co-stabilized Pickering emulsions with hierarchical interfacial structure: Enhanced stability and controllable lipolysis.
Yang Wei,Zhen Tong,Lei Dai,Peihua Ma,Mengfei Zhang,Jinfang Liu,Like Mao,Fang Yuan,Yanxiang Gao +8 more
TL;DR: The combination of nanoparticles and individual surfactants at the intermediate concentration exerted a synergistic effect on stabilizing the Pickering emulsions and inhibited lipolysis in the gastrointestinal tract, exhibiting potential applications as a fat replacer.
Journal ArticleDOI
Improvement on stability, loading capacity and sustained release of rhamnolipids modified curcumin liposomes.
Ce Cheng,Zhihua Wu,David Julian McClements,Liqiang Zou,Shengfeng Peng,Wei Zhou,Wei Zhou,Wei Liu +7 more
TL;DR: This study shows that rhamnolipids have great potential for liposomal delivery system suitable for utilization in functional foods, dietary supplements, and pharmaceutical preparations.
References
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Journal ArticleDOI
Microbial production of surfactants and their commercial potential.
JD Desai,Ibrahim M. Banat +1 more
TL;DR: Biosurfactants are more effective, selective, environmentally friendly, and stable than many synthetic surfactants, and the most promising applications are cleaning of oil-contaminated tankers, oil spill management, transportation of heavy crude oil, enhanced oil recovery, recovery of crude oil from sludge, and bioremediation of sites contaminated with hydrocarbons, heavy metals, and other pollutants.
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Environmental applications for biosurfactants
TL;DR: Biosurfactants are surfactants that are produced extracellularly or as part of the cell membrane by bacteria, yeast and fungi as mentioned in this paper, which are used for soil and water treatment.
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Assessment of the Alamar Blue assay for cellular growth and viability in vitro
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A new fluorometric assay for cytotoxicity measurements in-vitro
TL;DR: The use of Alamar Blue is described, a new non fluorescent substrate, which after reduction in living cells, yields a very strong fluorescent product and could be used with advantage for large scale in vitro screening of anticancer drugs and other cytotoxic agents.
Journal Article
Biosurfactants : Properties, commercial production and application
Krishnaswamy Muthusamy,Subbuchettiar Gopalakrishnan,Thiengungal Kochupappy Ravi,Panchaksharam Sivachidambaram +3 more
TL;DR: The role and applications of biosurfactants are discussed, focusing mainly on medicinal and therapeutic perspectives, including the use of cheaper raw materials, optimized and efficient bioprocesses and overproducing mutant and recombinant strains for obtaining maximum productivity.
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