Journal ArticleDOI
Sleep-related breathing disorders and pulmonary hypertension.
TLDR
The current knowledge of the consequences of SBDs on pulmonary haemodynamics in patients with and without chronic respiratory disease is considered and the effect of treatments of respiratory events during sleep on PH is considered.Citations
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Journal ArticleDOI
2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension.
Marc Humbert,Gábor L. Kovács,Marius M. Hoeper,Roberto Badagliacca,Rolf M. F. Berger,Margarita Brida,Jørn Carlsen,Andrew J.S. Coats,Pilar Escribano-Subías,Pisana Ferrari,Diogenes S. Ferreira,Hossein Ardeschir Ghofrani,Georgios Giannakoulas,David G. Kiely,Eckhard Mayer,Gergely Mészáros,B L Nagavci,Karen M. Olsson,Joanna Pepke-Zaba,Jennifer K Quint,Göran Rådegran,Gérald Simonneau,Olivier Sitbon,Thomy Tonia,Mark Toshner,Jean-Luc Vachiery,Anton Vonk Noordegraaf,Marion Delcroix,Stephan Rosenkranz +28 more
Journal ArticleDOI
2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
Marc Humbert,Gábor L. Kovács,Marius M. Hoeper,Roberto Badagliacca,Rolf M. F. Berger,Margarita Brida,Jørn Carlsen,Andrew J.S. Coats,Pilar Escribano-Subías,Pisana Ferrari,Diogenes S. Ferreira,Hossein Ardeschir Ghofrani,Georgios Giannakoulas,David G. Kiely,Eckhard Mayer,Gergely Mészáros,B L Nagavci,Karen M. Olsson,Joanna Pepke-Zaba,Jennifer K Quint,Göran Rådegran,Gérald Simonneau,Olivier Sitbon,Thomy Tonia,Mark Toshner,Jean-Luc Vachiery,Anton Vonk Noordegraaf,Marion Delcroix,Stephan Rosenkranz +28 more
TL;DR: The ESC/ERS pulmonary hypertension guidelines as mentioned in this paper incorporate changes and adaptations focusing on clinical management, which are made in consultation with the patient and caregiver as appropriate, based on what they consider to be the most appropriate in the circumstances.
Journal ArticleDOI
OSA and Chronic Respiratory Disease: Mechanisms and Epidemiology
TL;DR: Clinicians taking care of patients with chronic pulmonary disease should screen and treat patients for OSA, given the complex bidirectional relationship OSA has with chronic lung disease.
Journal ArticleDOI
Hypoxia in Aging and Aging-Related Diseases: Mechanism and Therapeutic Strategies
TL;DR: The role played by different degrees and types of hypoxia in aging and aging-related diseases and their possible pathways are elucidated, and rational treatment options based on such mechanisms for reference are proposed.
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Dysregulation of the Nitric Oxide/Dimethylarginine Pathway in Hypoxic Pulmonary Vasoconstriction—Molecular Mechanisms and Clinical Significance
TL;DR: Improved understanding of the molecular (dys-)regulation of pathways controlling ADMA concentration may help to dissect the pathophysiology and find novel therapeutic options for these diseases.
References
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Journal ArticleDOI
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).
Nazzareno Galiè,Marc Humbert,Jean-Luc Vachiery,Simon Gibbs,Irene Lang,Adam Torbicki,Gérald Simonneau,Andrew Peacock,Anton Vonk Noordegraaf,Maurice Beghetti,Ardeschir Ghofrani,Miguel Angel Gomez Sanchez,Georg Hansmann,Walter Klepetko,Patrizio Lancellotti,Marco Matucci,Theresa McDonagh,Luc Pierard,Pedro T. Trindade,Maurizio Zompatori,Marius M. Hoeper +20 more
TL;DR: In this paper, the authors defined the following terms: ALAT, alanine aminotransferase, ASAT, aspartate AMINOTE, and APAH, associated pulmonary arterial hypertension.
Journal ArticleDOI
Epidemiology of obstructive sleep apnea: a population health perspective.
TL;DR: Evidence from methodologically strong cohort studies indicates that undiagnosed obstructive sleep apnea, with or without symptoms, is independently associated with increased likelihood of hypertension, cardiovascular disease, stroke, daytime sleepiness, motor vehicle accidents, and diminished quality of life.
Journal ArticleDOI
Haemodynamic definitions and updated clinical classification of pulmonary hypertension.
Gérald Simonneau,Gérald Simonneau,David Montani,David Montani,David S. Celermajer,Christopher P. Denton,Michael A. Gatzoulis,Michael J. Krowka,Paul G. Williams,Rogério Souza +9 more
TL;DR: The 6th WSPH Task Force proposed to include pulmonary vascular resistance ≥3 Wood Units in the definition of all forms of pre-capillary PH associated with mPAP >20 mmHg, and included in group 1 of a subgroup “pulmonary arterial hypertension (PAH) long-term responders to calcium channel blockers”.
Journal ArticleDOI
ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension: A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: Developed in Collaboration With the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association
Vallerie V. McLaughlin,Stephen L. Archer,David B. Badesch,Robyn J. Barst,Harrison W. Farber,Jonathan R. Lindner,Michael A. Mathier,Michael D. McGoon,Myung H. Park,Robert S. Rosenson,Lewis J. Rubin,Victor F. Tapson,John Varga +12 more
TL;DR: In this paper, the authors discuss the role of the chairperson of FAHA and the chair's role in the FAHA Board of Trustee selection process and propose a new chairperson for FAHA.
Journal ArticleDOI
International classification of sleep disorders-third edition: highlights and modifications.
TL;DR: Significant modifications have been made to the nosology of insomnia, narcolepsy, and parasomnias in the recently released third edition of the International Classification of Sleep Disorders.