Journal ArticleDOI
Social stress-associated depression in adult female cynomolgus monkeys (Macaca fascicularis)
Carol A. Shively,Thomas C. Register,David Friedman,Timothy M. Morgan,Jalonda Thompson,Tasha Lanier +5 more
TLDR
This paper describes a behavior pattern in adult female cynomolgus monkeys that has several behavioral and physiological characteristics in common with human depression including reduced body fat, low levels of activity, high heart rate, hypothalamic-pituitary-adrenal (HPA) axis disturbances, and increased mortality.About:
This article is published in Biological Psychology.The article was published on 2005-04-01. It has received 132 citations till now. The article focuses on the topics: Social stress & Primate.read more
Citations
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Journal ArticleDOI
Why is depression more prevalent in women
TL;DR: This editorial focuses on biological contributors that are experimentally tractable and may help to understand how and why depression is more prevalent in women and lead to better treatments.
Journal ArticleDOI
Toward a neurology of loneliness.
TL;DR: Evidence that the perception of social isolation impacts brain and behavior and is a risk factor for broad-based morbidity and mortality is reviewed, highlighting the importance of integrating human and animal research to delineate the mechanisms through which social relationships impact the brain, health, and well-being.
Journal ArticleDOI
The role of defeat and entrapment in depression, anxiety, and suicide
TL;DR: There was evidence that perceptions of defeat and entrapment were closely associated with various forms of human psychopathology, and effects were often in the moderate to large range and superseded the impact of other environmental and psychological stressors on psychopathology.
Journal ArticleDOI
Necessity of Hippocampal Neurogenesis for the Therapeutic Action of Antidepressants in Adult Nonhuman Primates
Tarique D. Perera,Andrew J. Dwork,Kathryn Keegan,Lakshmi Thirumangalakudi,Cecilia M. Lipira,Niamh Joyce,Christopher S. Lange,J. Dee Higley,Gorazd Rosoklija,Gorazd Rosoklija,René Hen,Harold A. Sackeim,Jeremy D. Coplan +12 more
TL;DR: Exposing NHPs to repeated separation stress resulted in depression-like behaviors accompanied by reduced hippocampal neurogenesis, which likely plays a similar role in the treatment of clinical depression.
Journal ArticleDOI
Chronic Interferon- α Decreases Dopamine 2 Receptor Binding and Striatal Dopamine Release in Association with Anhedonia-Like Behavior in Nonhuman Primates
Jennifer C. Felger,Jiyoung Mun,Heather L. Kimmel,Heather L. Kimmel,Jonathon A. Nye,Daniel Drake,Carla R. Hernandez,Amanda A. H. Freeman,David B. Rye,Mark M. Goodman,Leonard L. Howell,Leonard L. Howell,Andrew H. Miller +12 more
TL;DR: Findings indicate that chronic peripheral IFN-α exposure reduces striatal DA release in association with anhedonia-like behavior in nonhuman primates and potential therapeutic strategies to reverse these changes are warranted.
References
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Journal ArticleDOI
Observational study of behavior: sampling methods.
TL;DR: Seven major types of sampling for observational studies of social behavior have been found in the literature and the major strengths and weaknesses of each method are pointed out.
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Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States: Results From the National Comorbidity Survey
Ronald C. Kessler,Katherine A. McGonagle,Shanyang Zhao,Christopher B. Nelson,Michael R. Hughes,Suzann Eshleman,Hans-Ulrich Wittchen,Kenneth S. Kendler +7 more
TL;DR: The prevalence of psychiatric disorders is greater than previously thought to be the case, and morbidity is more highly concentrated than previously recognized in roughly one sixth of the population who have a history of three or more comorbid disorders.
Journal ArticleDOI
Socioeconomic status and health: The challenge of the gradient.
Nancy E. Adler,Thomas Boyce,Margaret A. Chesney,Sheldon Cohen,Susan Folkman,Robert L. Kahn,S. Leonard Syme +6 more
TL;DR: There is evidence of a graded association with health at all levels of SES, an observation that requires new thought about domains through which SES may exert its health effects.
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Socioeconomic status and health: what we know and what we don't.
Nancy E. Adler,Joan M. Ostrove +1 more
TL;DR: This paper examines the data regarding the SES‐health gradient, addressing causal direction, generalizability across populations and diseases, and associations with health for different indicators of SES.
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Altered Pituitary-Adrenal Axis Responses to Provocative Challenge Tests in Adult Survivors of Childhood Abuse
TL;DR: Abused women without major depressive disorder exhibited greater than usual ACTH responses to CRF administration, whereas abused women with major de...