Journal ArticleDOI
Social Stress-Induced Behavioral Adaptations in Females: A Focus on Midline Thalamus Crh Neurons.
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This article is published in Biological Psychiatry.The article was published on 2021-10-15. It has received 0 citations till now. The article focuses on the topics: Social stress.read more
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Journal ArticleDOI
Lifetime Co-occurrence of DSM-III-R Alcohol Abuse and Dependence With Other Psychiatric Disorders in the National Comorbidity Survey
Ronald C. Kessler,Rosa M. Crum,Lynn A. Warner,Christopher B. Nelson,John E. Schulenberg,James C. Anthony +5 more
TL;DR: The results show that alcohol abuse and dependence are often associated with other lifetime NCS/DSM-III-R disorders and suggest that, at least in recent cohorts, the alcohol use disorders are usually temporally secondary.
Journal ArticleDOI
Establishment of a repeated social defeat stress model in female mice
Aki Takahashi,Aki Takahashi,Aki Takahashi,Jia Ru Chung,Song Zhang,Hongxing Zhang,Yael S. Grossman,Hossein Aleyasin,Meghan E. Flanigan,Madeline L. Pfau,Caroline Menard,Dani Dumitriu,Georgia E. Hodes,Bruce S. McEwen,Eric J. Nestler,Ming-Hu Han,Scott J. Russo +16 more
TL;DR: A female mouse model of RSDS is established by inducing male aggression toward females through chemogenetic activation of the ventrolateral subdivision of the Ventromedial hypothalamus (VMHvl) to demonstrate that females susceptible to RSDS display social avoidance, anxiety-like behavior, reduction of body weight, and elevated levels of circulating interleukin 6.
Journal ArticleDOI
A Novel Method for Chronic Social Defeat Stress in Female Mice
Alexander Z. Harris,Piray Atsak,Zachary H. Bretton,Emma S Holt,Raisa Alam,Mitchell P. Morton,Atheir I. Abbas,E. David Leonardo,Scott S. Bolkan,René Hen,Joshua A. Gordon,Joshua A. Gordon +11 more
TL;DR: A new version of the social defeat paradigm that works in female mice is reported, and it is found that female mice undergo repeated social defeat stress and develop social avoidance, decreased sucrose preference, and decreased time in the open arms of the elevated plus maze relative to control mice.
Journal ArticleDOI
Fighting Females: Neural and Behavioral Consequences of Social Defeat Stress in Female Mice.
Emily L. Newman,Herbert E. Covington,Junghyup Suh,Matthew B. Bicakci,Kerry J. Ressler,Joseph F. DeBold,Klaus A. Miczek +6 more
TL;DR: These findings demonstrate that CFW female mice living with male conspecifics can be used as aggressive residents in an ethological model of female social defeat stress, and will encourage further studies of sex-specific neural, physiological, and behavioral adaptations to chronic stress and the biological bases for interfemale aggression.
Journal ArticleDOI
Two genetically, anatomically and functionally distinct cell types segregate across anteroposterior axis of paraventricular thalamus
Claire Gao,Claire Gao,Yan Leng,Jun Ma,Victoria Rooke,Shakira Rodriguez-Gonzalez,Charu Ramakrishnan,Karl Deisseroth,Mario A. Penzo +8 more
TL;DR: The results uncover the existence of an arousal-modulated thalamo-corticothalamic loop that links the PVT and the ventromedial prefrontal cortex and provide evidence that two major classes of neurons exist in the paraventricular thalamus.