Journal ArticleDOI
Solution Properties of Poly(N-isopropylacrylamide)
M. Heskins,J. E. Guillet +1 more
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TLDR
In this paper, a lower critical solution temperature of poly(N-isopropyl acrylamide was found to be due to an entropy effect, which was attributed to the formation of nonpolar and intermolecular hydrogen bonds.Abstract:
Aqueous solutions of poly(N-isopropyl acrylamide) show a lower critical solution temperature. The thermodynamic properties of the system have been evaluated from the phase diagram and the heat absorbed during phase separation and the phenomenon is ascribed to be primarily due to an entropy effect. From viscosity, sedimentation, and light-scattering studies of solutions close to conditions of phase separation, it appears that aggregation due to formation of nonpolar and intermolecular hydrogen bonds is important. In addition, a weakening of the ordering effect of the water-amide hydrogen bonds as the temperature is raised contributes to the stability of the two-phase system.read more
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Book ChapterDOI
Contemporary Topics in Polymeric Materials for Biomedical Applications
TL;DR: In this paper, a review of polymeric materials for biomedical applications is presented, with the emphasis on the modes of interaction of water soluble polymers as well as their conjugates, and those of microdomain-structured polymers with proteins and cells.
Journal ArticleDOI
Transiently thermoresponsive polymers and their applications in biomedicine
TL;DR: An overview of the different approaches used for the design of these polymers along with their physicochemical properties is given, which make this class of responsive polymers attractive for drug delivery and tissue engineering applications.
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Thermoresponsive Toughening with Crack Bifurcation in Phase-Separated Hydrogels under Isochoric Conditions
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Local drug delivery in restenosis injury: thermoresponsive co-polymers as potential drug delivery systems.
TL;DR: In this article, the authors focus on properties of a class of environment-sensitive hydrogels, the N-isopropylacrylamide-based thermoresponsive co-polymers, on their potential roles as stent coatings, and on their demonstrated ability to incorporate and release drugs that modify vascular endothelial and smooth muscle cell functions.
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Journal ArticleDOI
Mouvement Brownien d'un ellipsoide (II). Rotation libre et dépolarisation des fluorescences. Translation et diffusion de molécules ellipsoidales
TL;DR: In this article, the diffusion of molecules ellipsoidales dissoutes is analyzed in a mouvement brownien d'ensemble (rotation and translation) with respect to a set of molecules.
Journal ArticleDOI
The thermodynamic properties of aqueous solutions of polyethylene glycol, polypropylene glycol and dioxane
G. N. Malcolm,J. S. Rowlinson +1 more
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Thermodynamics of polyisobutylene-n-alkane systems
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