Stimulation of esterified cholesterol accumulation in tissue culture cells exposed to high density lipoproteins enriched in free cholesterol.
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TLDR
The data indicate that the lipid composition of a lipoprotein can regulate free cholesterol uptake and esterification as well as cellular cholesterol content.About:Â
This article is published in Journal of Lipid Research.The article was published on 1978-03-01 and is currently open access. It has received 88 citations till now. The article focuses on the topics: Very low-density lipoprotein & Reverse cholesterol transport.read more
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Use of cyclodextrins for manipulating cellular cholesterol content.
TL;DR: The methylated beta-cyclodextrin was found to be a more efficient donor in all cell types studied, with an average cholesterol uptake of at least 100 microg cholesterol/mg protein within 6 h.
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Mechanisms and consequences of cellular cholesterol exchange and transfer
TL;DR: The influence of enzymes such as lecithin-cholesterol acyltransferase and hepatic lipase on the direction of net transfer of free cholesterol between lipoproteins and cells can be understood in terms of their effects on the pool sizes and the rate constants for influx and efflux.
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Cholesterol transport between cells and high-density lipoproteins.
TL;DR: The most prominent and easily measured aspect of sterol movement between HDL and cells is the rapid bidirectional transfer of cholesterol between the lipoprotein and the plasma membrane.
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A survey of 246 suggested coronary risk factors
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
A rapid method of total lipid extraction and purification.
E. G. Bligh,W. J. Dyer +1 more
TL;DR: The lipid decomposition studies in frozen fish have led to the development of a simple and rapid method for the extraction and purification of lipids from biological materials that has been applied to fish muscle and may easily be adapted to use with other tissues.
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The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
TL;DR: The relatively low density of the lipoproteins was utilized by Lindgren, Elliott, and Gofman to separate them from the other serum proteins by ultracentrifugal flotation, and quantitation was subsequently performed by refractometric methods in the analytical ultracentRifuge.
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The metabolism of very low density lipoprotein proteins. I. Preliminary in vitro and in vivo observations.
TL;DR: During the first 24 h after injection of 125I-labeled very low density lipoprotein to humans, the decay rate of low densitylipoprotein apoprotein from very lowdensity lipoproteins was faster than that of apolipoprotein glutamic acid, apoipoprotein alanine1 and apolipropoteinAlanine2.
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