Journal ArticleDOI
Structural studies of the Vibrio cholerae O-antigen
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TLDR
Treatment of the N-deacylated polysaccharide with nitrous acid caused deamination with concomitant rearrangements, typical of 4-amino-4-deoxyhexopyranosyl residues in which the amino group occupies an equatorial position.About:
This article is published in Carbohydrate Research.The article was published on 1979-01-01. It has received 134 citations till now. The article focuses on the topics: Homopolysaccharide & Amino sugar.read more
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Journal ArticleDOI
New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development.
TL;DR: A review of available information leads to the conclusion that an oral vaccine consisting of a combination of antigens, intending to stimulate both antibacterial and antitoxic immunity, would be most likely to succeed.
Book ChapterDOI
Lipopolysaccharides of Gram-Negative Bacteria
Otto Lüderitz,Marina A. Freudenberg,Chris Galanos,Volker Lehmann,Ernst Th. Rietschel,Derek H. Shaw +5 more
TL;DR: The studies indicate that at least some lipid A activities are not restricted to one specific structure, but are rather connected with general physicochemical properties.
Journal ArticleDOI
Vibrio cholerae and cholera: Out of the water and into the host
Joachim Reidl,Karl E. Klose +1 more
TL;DR: This review provides an overview of the current knowledge of both the host- and environment-specific physiological attributes of V. cholerae.
Journal ArticleDOI
Structure of the O‐chain of the phenol‐phase soluble cellular lipopolysaccharide of Yersinia enterocolitica serotype O:9
TL;DR: The serological cross-reactivity between Y. enterocolitica serotype O:9 and the lipopolysaccharides of Vibrio cholerae and Brucella species can now be related to the presence of N-acylated 4-amino-4,6-dideoxy-alpha-D-mannopyranosyl residues in their respective O-antigenic chains.
Journal ArticleDOI
Characterization of Vibrio cholerae O1 El Tor galU and galE Mutants: Influence on Lipopolysaccharide Structure, Colonization, and Biofilm Formation
TL;DR: It is found that galU and galE are essential for the formation of a biofilm in a spontaneous phage-resistant rugose variant, suggesting that the synthesis of UDP-galactose via UDP-glucose is necessary for biosynthesis of the exopolysaccharide.
References
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Journal ArticleDOI
Anhydrous hydrogen fluoride deglycosylates glycoproteins.
TL;DR: During the cleavage of glycosidic linkages by anhydrous hydrogen fluoride there is little or no degradation of the sugars themselves, thus allowing their quantitative recovery, which may also be useful in the analysis of complex polysaccharides.
Book ChapterDOI
Deamination of Carbohydrate Amines and Related Compounds
TL;DR: In this article, an attempt is made to rationalize the different kinds of behavior of carbohydrate amines, including the cyclitol amines upon deamination, and the potential use and limitations of these reactions in synthesis and elucidation of structure are discussed.
Journal ArticleDOI
Dextrans as test molecules in studies of the functional ultrastrucutre of biological membranes. Molecular weight distribution analysis by gel chromatography.
Gösta Arturson,Kirsti Granath +1 more
TL;DR: A detailed procedure for the gel chromatographic molecular weight distribution analysis of dextran in different biological fluids is presented together with the results obtained on applying the method to studies on membrane structures.
Journal ArticleDOI
The structure of the O-antigenic side chain of the lipopolysaccharide of Vibrio cholerae 569B (Inaba).
TL;DR: Mineral acid hydrolysis of the lipopolysaccharide from Vibrio cholerae 569B (Inaba) gives an oligosaccharide fraction which was shown to be a regular alpha-(1 leads to 2) linked chain of D-perosamine (4-amino-4,6-dideoxy-D-mannose) units.
Journal ArticleDOI
2-Amino-2,6-dideoxy-d-glucose (D-quinovosamine): a constituent of the lipopolysaccharides of Vibrio cholerae.
TL;DR: From the lipopolysaccharides of Vibrio cholerae strains Inaba and Ogawa, an unusual amino sugar was isolated and identified as 2-amino-2,6-dideoxyglucose (quinovosamine), its optical rotation indicated it to be of the d- configuration.