Studies on phospholipase a and its zymogen from porcine pancreas IV. The influence of chemical modification of the lecithin structure on substrate properties
TLDR
In this article, a series of chemically modified lecithins were used to investigate by kinetic analyses their substrate c.q. inhibitor properties for porcine pancreatic phospholipase A.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1972-07-07 and is currently open access. It has received 186 citations till now. The article focuses on the topics: Moiety & Phospholipid.read more
Citations
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Journal ArticleDOI
Biomolecular interactions at phospholipid-decorated surfaces of liquid crystals
TL;DR: These results provide principles for label-free monitoring of aqueous streams for molecular and biomolecular species without the need for complex instrumentation.
Journal ArticleDOI
Action of phospholipase A at interfaces.
TL;DR: A quantitative comparison between enzyme kinetics obtained by monolayer and bulk techniques is attempted using a common definition of the "quality" of the lipid-water interface, and the concept of a penetration site on the enzyme is discussed.
Book ChapterDOI
Structure and function of phospholiphase A2
Journal ArticleDOI
Histidine at the active site of phospholipase A2
References
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Journal ArticleDOI
The characteristics of mixed micellar solutions with particular reference to bile
Martin C. Carey,Donald Small +1 more
TL;DR: Lipids are classified into soluble and insoluble species and it is suggested, as far as is presently possible, how soluble lipids form mixed micelles with insoluble lipids.
Journal ArticleDOI
The inhibition of arginase by amino acids
Andrew Hunter,Clarence E. Downs +1 more
TL;DR: Investigating quantitatively the effect upon arginase activity of a fairly large series of amino acids and of some amino acid derivatives has proved to be not only of practical, but also of considerable theoretical interest.
Journal ArticleDOI
The substrate specificity of phospholipase a.
L.L.M. Van Deenen,G.H. de Haas +1 more
TL;DR: Investigations on variously modified analogues of phospholipids elucidated the following substrate characteristics forospholipase A (Crotalus adamanteus): l-α-Lecithins containing fatty acids with greatly varying chain length are susceptible to phospholIPase A action; however, certain water-soluble short-chain compounds are hydrolysed at a very slow rate only.
Journal ArticleDOI
Synthesis of lecithins by acylation of O-(sn-glycero-3-phosphoryl) choline with fatty acid anhydrides
E.Cubero Robles,D. Van Den Berg +1 more
TL;DR: A new method has been developed for the partial synthesis of saturated, unsaturated and mixed-acid lecithins using the free O-(sn-glycero-3-phosphoryl) choline and its CdCl2 complex as starting materials.
Journal ArticleDOI
Studies on phospholipase A and its zymogen from porcine pancreas: III. Action of the enzyme on short-chain lecithins
TL;DR: In this paper, short-chain lecithins with C6, C7, and C8 fatty acid esters have been used to study kinetically the enzymatic hydrolysis by pancreatic phospholipase A (EC 3.4) in aqueous systems, without the addition of emulsifiers.