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Journal ArticleDOI

Substance use disorders in schizophrenia: review, integration, and a proposed model.

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TLDR
Little empirical support is found for models suggesting that schizophrenic symptoms lead to substance use (self-medication), that substance use leads to schizophrenia, or that there is a genetic relationship between schizophrenia and substance use.
About
This article is published in Clinical Psychology Review.The article was published on 2000-03-01. It has received 228 citations till now. The article focuses on the topics: Schizophrenia (object-oriented programming) & Substance abuse.

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Citations
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The Self-medication Hypothesis of Substance Use Disorders: A Reconsideration and Recent Applications

TL;DR: The self-medication hypothesis of addictive disorders derives primarily from clinical observations of patients with substance use disorders as mentioned in this paper, who discover that the specific actions or effects of each class of drugs relieve or change a range of painful affect states.
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Binge drinking trajectories from adolescence to emerging adulthood in a high-risk sample: predictors and substance abuse outcomes.

TL;DR: All 3 drinking trajectory groups raised risk for later substance abuse or dependence compared with the nonbingers, with the early-heavy group at highest risk.
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Randomized controlled trial of motivational interviewing, cognitive behavior therapy, and family intervention for patients with comorbid schizophrenia and substance use disorders.

TL;DR: These findings demonstrate the effectiveness of a program of routine care integrated with motivational interviewing, cognitive behavior therapy, and family intervention over routine psychiatric care alone for patients with comorbid schizophrenia and alcohol or drug abuse or dependence.
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The impact of substance use disorders on clinical outcome in 643 patients with first-episode psychosis.

TL;DR: The main aim of the present study was to assess the impact of baseline SUD and course of SUD on remission of positive symptoms.
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Comorbid substance use and age at onset of schizophrenia

TL;DR: The strong association between self-reported Cannabis use and earlier onset of psychosis provides further evidence that schizophrenia may be precipitated by cannabis use and/or that the early onset of symptoms is a risk factor for cannabis use.
References
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Assessing Coping Strategies: A Theoretically Based Approach

TL;DR: A multidimensional coping inventory to assess the different ways in which people respond to stress was developed and an initial examination of associations between dispositional and situational coping tendencies was allowed.
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Comorbidity of Mental Disorders With Alcohol and Other Drug Abuse. Results From the Epidemiologic Catchment Area (ECA) Study

TL;DR: Comorbidity of addictive and severe mental disorders was highest in the prison population, most notably with antisocial personality, schizophrenia, and bipolar disorders.
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Negative affectivity: The disposition to experience aversive emotional states

TL;DR: A number of apparently diverse personality scales—variously called trait anxiety, neuroticism, ego strength, general maladjustment, repression-sensitization, and social desirability—are reviewed and are shown to be in fact measures of the same stable and pervasive trait.
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If it changes it must be a process: Study of emotion and coping during three stages of a college examination.

TL;DR: This natural experiment provides substantial evidence for the following major themes, which are based on a cognitively oriented, process-centered theory of stress and coping: First, a stressful encounter should be viewed as a dynamic, unfolding process, not as a static, unitary event.
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Neurogenetic adaptive mechanisms in alcoholism

TL;DR: In this paper, three dimensions of personality have been described that may reflect individual differences in brain systems modulating the activation, maintenance, and inhibition of behavioral responses to the effects of alcohol and other environmental stimuli.
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