Open AccessJournal Article
Swerchirin induced blood sugar lowering of streptozotocin treated hyperglycemic rats.
Reads0
Chats0
TLDR
Effect of Swerchirin (1:8 dihydroxy 3:5 dimethoxy xanthone) isolated from hexane fraction of Swertia chirayita on the blood sugar level of healthy and streptozotocin treated rats was studied.Abstract:
Effect of Swerchirin (1:8 dihydroxy 3:5 dimethoxy xanthone) isolated from hexane fraction of Swertia chirayita on the blood sugar level of healthy and streptozotocin treated rats was studied. Streptozotocin was administered in citrate buffer (pH-4.5) intravenously / 35 and 65 mg/kg body wt to Charles Foster strain albino rats. Swerchirin (50 mg/kg, po) suspended in gum acacia was fed through cannula to the above rats and to a group of healthy rats. Blood sugar estimated at 0, 1, 3 and 7 hr after, indicated a very significant lowering in healthy and streptozotocin (35 mg/kg iv) but not in streptozotocin (65 mg/kg) treated rats.read more
Citations
More filters
Journal ArticleDOI
Medicinal plants of India with anti-diabetic potential.
J.K Grover,S.P Yadav,V Vats +2 more
TL;DR: 45 plants and their products that have been mentioned/used in the Indian traditional system of medicine and have shown experimental or clinical anti-diabetic activity are reviewed.
Journal ArticleDOI
Leads from Indian medicinal plants with hypoglycemic potentials
TL;DR: This article aims to provide a comprehensive review on various plant species from Indian biosphere and their constituents, which have been shown to display potent hypoglycemic activity.
Journal ArticleDOI
Medicinal plants with potential antidiabetic activity - a review of ten years of herbal medicine research (1990-2000)
TL;DR: This review presents the profiles of plants with hypoglycaemic properties, reported in the literature from 1990 to 2000, to demonstrate the importance of herbal plants in the treatment of diabetes mellitus and shows the effort to isolate new potential antidiabetic agents.
Journal ArticleDOI
A Review of Swertia chirayita (Gentianaceae) as a Traditional Medicinal Plant.
Vijay Kumar,Johannes Van Staden +1 more
TL;DR: The aim of this review is to provide a synthesis of the current state of scientific knowledge on the medicinal uses, phytochemistry, pharmacological activities, safety evaluation as well as the potential role of plant biotechnology in the conservation of Swertia chirayita and to highlight its future prospects.
Journal ArticleDOI
Medicinal plant species with potential antidiabetic properties.
TL;DR: In this review, selected species that have been validated for their hypoglycaemic or antihyperglycaemic properties using laboratory diabetic animal models and in clinical trials using human subjects, and reported in refereed journals are presented.