Journal ArticleDOI
Synthesis of Cinnolin-3(2H)-one Derivatives from Rh-Catalyzed Reaction of Azobenzenes with Diazotized Meldrum's Acid.
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TLDR
A synthetic method of a wide range of cinnolin-3(2H)-one derivatives is developed from the reaction of symmetrical as well as unsymmetrical azobenzenes with diazotized Meldrum's acid via Rh-catalyzed C-H alkylation followed by cyclization.About:
This article is published in Organic Letters.The article was published on 2015-05-01. It has received 96 citations till now. The article focuses on the topics: Meldrum's acid & Alkylation.read more
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Transition-Metal-Catalyzed Cross-Couplings through Carbene Migratory Insertion
Ying Xia,Di Qiu,Jianbo Wang +2 more
TL;DR: This review will summarize the achievements made in cross-coupling area since 2001 and identify the new organometallic species generated from migratory insertion that may undergo various transformations.
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Diazo Compounds: Versatile Synthons for the Synthesis of Nitrogen Heterocycles via Transition Metal‐Catalyzed Cascade C–H Activation/Carbene Insertion/Annulation Reactions
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RhIII‐Catalyzed CH Activation with Pyridotriazoles: Direct Access to Fluorophores for Metal‐Ion Detection
TL;DR: The first C-H bond activation with pyridotriazoles as coupling partners is presented using a Rh(III) catalyst and these tunable fluorophores can be applied for the detection of metal ions.
Journal ArticleDOI
Regio-selective synthesis of diversely substituted benzo[a]carbazoles through Rh(iii)-catalyzed annulation of 2-arylindoles with α-diazo carbonyl compounds.
TL;DR: To the authors' knowledge, this is the first example in which the NH unit of indole is used as a directing group for an intramolecular C(sp2)-H bond functionalization to give benzo[a]carbazole derivatives.
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Regioselective synthesis of multisubstituted isoquinolones and pyridones via Rh(III)-catalyzed annulation reactions.
TL;DR: A mild and efficient Rh(III)-catalyzed regioselective synthesis of isoquinolones and pyridones and derivatives containing various functional groups has been developed.
References
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Book
Comprehensive Heterocyclic Chemistry II
TL;DR: In this article, the CHEC III is organized in 15 volumes and closely follows the organization used in the previous edition: Volumes 1 and 2: Cover respectively three and four-membered heterocycles, together with all fused systems containing a three- or four-measured heterocyclic ring.
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A Coupling of Benzamides and Donor/Acceptor Diazo Compounds To Form γ-Lactams via Rh(III)-Catalyzed C–H Activation
TL;DR: Mechanistic experiments suggested that C-H activation is turnover-limiting and irreversible and that insertion of the diazo compound favors electron-deficient substrates.
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Rh-catalyzed intermolecular carbenoid functionalization of aromatic C-H bonds by α-diazomalonates.
TL;DR: In most cases, arenes with oximes, carboxylic acids, and amines as directing groups cross-couple with diazomalonates with excellent regioselectivities and functional group tolerance, and thus, this reaction offers a new route to α-aryl carbonyl compounds for specific applications.
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Rh(III)-catalyzed synthesis of multisubstituted isoquinoline and pyridine N-oxides from oximes and diazo compounds.
TL;DR: This intermolecular annulation involving tandem C-H activation, cyclization, and condensation steps proceeds under mild conditions, obviates the need for oxidants, releases N2 and H2O as the byproducts, and displays a broad substituent scope.
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Rh(III)-catalyzed C–H activation/[4 + 3] cycloaddition of benzamides and vinylcarbenoids: facile synthesis of azepinones
TL;DR: In this paper, a kinetic isotope effect study was conducted and a plausible mechanism was proposed for cycloaddition with benzamides to access azepinones, which makes a feature of simple starting materials, mild reaction conditions and high efficiency.