Journal ArticleDOI
Target blood pressure in patients at high cardiovascular risk
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This article is published in The Lancet.The article was published on 2017-06-03. It has received 1 citations till now. The article focuses on the topics: Aortic pressure & Blood pressure.read more
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Blood pressure goals: A moving target
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Journal ArticleDOI
Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies.
TL;DR: Throughout middle and old age, usual blood pressure is strongly and directly related to vascular (and overall) mortality, without any evidence of a threshold down to at least 115/75 mm Hg.
Journal ArticleDOI
A Randomized Trial of Intensive versus Standard Blood-Pressure Control
Jackson T. Wright,Jeff D. Williamson,Paul K. Whelton,Joni K. Snyder,Kaycee M. Sink,Michael V. Rocco,David M. Reboussin,Mahboob Rahman,Mahboob Rahman,Suzanne Oparil,Cora E. Lewis,Paul L. Kimmel,Karen C. Johnson,David C. Goff,Lawrence J. Fine,Jeffrey A. Cutler,William C. Cushman,Alfred K. Cheung,Walter T. Ambrosius +18 more
TL;DR: In this article, the most appropriate targets for systolic blood pressure to reduce cardiovascular morbidity and mortality among persons without diabetes remain uncertain, and the authors propose a target of less than 120 mm Hg.
Journal ArticleDOI
A Randomized Trial of Intensive versus Standard Blood-Pressure Control.
TL;DR: Among patients at high risk for cardiovascular events but without diabetes, targeting a systolic blood pressure target of less than 120 mm Hg, as compared with less than 140 mm HG, resulted in lower rates of fatal and nonfatal major cardiovascular events and death from any cause, although significantly higher rates of some adverse events were observed in the intensive-treatment group.
Journal ArticleDOI
Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people.
Eleni Rapsomaniki,Adam Timmis,Julie George,Mar Pujades-Rodriguez,Anoop D. Shah,Spiros Denaxas,Ian R. White,Mark J. Caulfield,John E. Deanfield,Liam Smeeth,Bryan Williams,Aroon D. Hingorani,Harry Hemingway +12 more
TL;DR: The widely held assumptions that blood pressure has strong associations with the occurrence of all cardiovascular diseases across a wide age range, and that diastolic and systolic associations are concordant, are not supported by the findings of this high-resolution study.
Journal ArticleDOI
Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis
Xinfang Xie,Emily Atkins,Jicheng Lv,Jicheng Lv,Alexander I. Bennett,Bruce Neal,Toshiharu Ninomiya,Mark Woodward,Stephen MacMahon,Fiona Turnbull,Graham S. Hillis,John Chalmers,Jonathan Mant,Abdul Salam,Kazem Rahimi,Vlado Perkovic,Anthony Rodgers +16 more
TL;DR: The reduction in major cardiovascular events was consistent across patient groups, and additional blood pressure lowering had a clear benefit even in patients with systolic blood pressure lower than 140 mm Hg.