Journal ArticleDOI
Testosterone, androstenedione and dihydrotestosterone: Effects on mating behavior of male rats
TLDR
It was concluded that the peripherally active steroid dihydrotestosterone probably plays no role in the maintenance of sexual behavior and can be accumulated by brain and peripheral androgen-sensitive tissues.About:
This article is published in Hormones and Behavior.The article was published on 1971-06-01. It has received 164 citations till now. The article focuses on the topics: Androstenedione & Dihydrotestosterone.read more
Citations
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Book ChapterDOI
Male Sexual Behavior
TL;DR: Major areas controlling sexual motivation and performance in males include the mesolimbic dopamine (DA) system, the medial preoptic area (MPOA), the amygdala, and the bed nucleus of the stria terminalis (BST).
Book ChapterDOI
Steroid Hormone Receptors
TL;DR: The dependence of human cancers on hormones, the detection and characterization of steroid receptor interactions, and the physiological and pharmacological implications of steroid hormone receptors are discussed.
Journal ArticleDOI
Copulation in Castrated Male Rats following Combined Treatment with Estradiol and Dihydrotestosterone
TL;DR: Castrated male rats injected daily with 2 micrograms of estradiol benzoate (EB) combined with 200 microgramS of dihydrotestosterone propionate (DHTP) displayed masculine mating behavior which was indistinguishable from that of other castrates treated with 200 milligrams of testosterone propionates.
Book
The Mechanism of Action of Androgens
TL;DR: A contemporary model for the Mechanism of Action of Androgen Action is presented, focusing on the Uptake, Retention, and Release of Androgens on Rat Ventral Prostate Gland and the Androgenic Regulation of RNA Synthesis: Receptor Effects in vitro.
Journal ArticleDOI
Neural control of erection.
F. Giuliano,Olivier Rampin +1 more
TL;DR: The spinal cord contains the autonomic preganglionic neurons that innervate the penile erectile tissue and the pudendal motoneurons that stimulate the perineal striated muscles as mentioned in this paper.
References
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Journal ArticleDOI
Selective retention of dihydrotestosterone by prostatic nuclei
K. M. Anderson,Shutsung Liao +1 more
TL;DR: Nuclear chromatin of prostate, but not other tissues which are insensitive to androgen, contains an androgen receptor which can selectively retain dihydrotestosterone (DHT, 5α-androstane-17β-ol-3-one)—the most potent endogenous androgen for the growth of ventral prostate of rat13,14.
Journal ArticleDOI
The intranuclear binding of testosterone and 5-alpha-androstan-17-beta-ol-3-one by rat prostate.
TL;DR: It was shown that dihydrotestosterone was bound to an acidic nuclear protein and was stable to freezing for as long as 8 days, stable to short term incubation at 20° but not at 37°, and partially stable to repeated gel filtration on Sephadex.
Journal ArticleDOI
Androgen concentrations in plasma and testis of developing rats.
Journal ArticleDOI
A comparative study of the conversion of testosterone to 17-beta-hydroxy-5-alpha-androstan-3-one (Dihydrotestosterone) by prostate and epididymis.
Robert E. Gloyna,Jean D. Wilson +1 more
TL;DR: Dihydrotestosterone formation was measurable in all of the immature prostates studied, including that from calf, and in a variety of other tissues known to be under androgenic control—duck preen gland, the comb and wattle of the chicken, and the preputial gland of rat and mouse.
Journal ArticleDOI
Failure of 5α-Dihydrotestosterone to initiate Sexual Behaviour in the Castrated Male Rat
P. Mcdonald,Carlos Beyer,F. Newton,B. Brien,R. Baker,H. S. Tan,C. Sampsom,P. Kitching,R. Greenhill,D. Pritchard +9 more
TL;DR: The failure of 5-DHT to initiate sexual behaviour in the castrated male rat is concerned, which suggests that the aromatization of androgens may be of significance in the activation of sexual behaviour.