Journal ArticleDOI
The binding of fatty acids to cytoplasmic proteins: binding to Z protein in liver and other tissues of the rat.
Reads0
Chats0
TLDR
A cytoplasmic binding protein (Z protein) has been shown to have a high affinity for fatty acids in rat liver, myocardium, skeletal muscle, intestinal mucosa, adipose tissue and kidney.About:
This article is published in Biochemical and Biophysical Research Communications.The article was published on 1972-06-09. It has received 247 citations till now. The article focuses on the topics: Fatty acid & Binding protein.read more
Citations
More filters
Journal ArticleDOI
Fatty acid binding to plasma albumin.
TL;DR: A review of the available information about fatty acid binding to plasma albumin is presented, and stepwise association constants for binding to human albumin of fatty acids containing 6-18 carbon atoms indicate that each mole of fatty acid binds with a different affinity.
Book ChapterDOI
The Glutathione S‐Transferases: A Group of Multifunctional Detoxification Proteins
TL;DR: There appears to be sufficient enzyme for all three roles in detoxification of glutathione S-transferases; the binding of bilirubin is an example of a major function common to all higher species.
Journal ArticleDOI
Enterohepatic circulation: physiological, pharmacokinetic and clinical implications.
TL;DR: Enterohepatic recycling occurs by biliary excretion and intestinal reabsorption of a solute, sometimes with hepatic conjugation and intestinal deconjugation, and may prolong the pharmacological effect of certain drugs and drug metabolites.
Journal ArticleDOI
beta-oxidation of fatty acids in mitochondria, peroxisomes, and bacteria: a century of continued progress.
Journal ArticleDOI
The fatty acid transport function of fatty acid-binding proteins.
Judith Storch,Alfred E. Thumser +1 more
TL;DR: Data from a number of experimental approaches have provided strong support for defining the FABPs as fatty acid transport proteins, and further studies are necessary to elucidate the fundamental mechanisms by which cellular fatty acid trafficking is modulated by theFABPs.
References
More filters
Journal ArticleDOI
The Determination of Enzyme Dissociation Constants
Hans Lineweaver,Dean Burk +1 more
TL;DR: On the basis of the assumed theory the rate of the observed reaction is directly proportional to the concentration of the enzyme-substrate compound, where (E:l = (ES).
Journal ArticleDOI
Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions
TL;DR: Two hepatic cytoplasmic protein fractions, designated Y and Z, which bind sulfobromophthalein (BSP), bilirubin, and other organic anions, have been separated by G75 Sephadex gel filtration and appear to be important in the transfer of Organic anions from plasma into the liver.
Journal ArticleDOI
Ligandin: a Hepatic Protein which Binds Steroids, Bilirubin, Carcinogens and a Number of Exogenous Organic Anions
TL;DR: Three protein preparations from the rat liver 100,000g supernatant fraction have been independently purified to homogeneity, and they are basic azodye carcinogen-binding protein (β-ABP), corticosteroid Binder I3,4 and Y protein5.
Journal ArticleDOI
Tissue distribution of c14 after the intravenous injection of labeled chylomicrons and unesterified fatty acids in the rat
Journal ArticleDOI
Studies of Y and Z, two hepatic cytoplasmic organic anion-binding proteins: effect of drugs, chemicals, hormones, and cholestasis
TL;DR: The hypothesis that Y and Z are involved in the transfer of BSP, ICG, and possibly other organic anions from plasma into the liver is supported.
Related Papers (5)
A binding protein for fatty acids in cytosol of intestinal mucosa, liver, myocardium, and other tissues.
Two hepatic cytoplasmic protein fractions, Y and Z, and their possible role in the hepatic uptake of bilirubin, sulfobromophthalein, and other anions
Fatty Acid-Binding Protein in Small Intestine IDENTIFICATION, ISOLATION, AND EVIDENCE FOR ITS ROLE IN CELLULAR FATTY ACID TRANSPORT
Robert K. Ockner,Joan A. Manning +1 more