Journal ArticleDOI
The carcinogenic potency of carbon particles with and without PAH after repeated intratracheal administration in the rat.
Reads0
Chats0
TLDR
The role of carcinogenic PAH in soot- and carbon black-related lung tumour induction in rats was investigated after intratracheal administration of carbon blacks and two types of diesel soot, either as original or as toluene extracted particles.About:
This article is published in Toxicology Letters.The article was published on 1996-11-01. It has received 65 citations till now.read more
Citations
More filters
Posted Content
Nanomaterials and nanoparticles: Sources and toxicity
TL;DR: A review of the toxicity of nanoparticles is presented in this paper, with the goal of informing public health concerns related to nanoscience while raising awareness of nanomaterials toxicity among scientists and manufacturers handling them.
Journal ArticleDOI
Nanomaterials and nanoparticles: Sources and toxicity
TL;DR: This review reveals the result of life’s long history of evolution in the presence of nanoparticles, and how the human body has adapted to defend itself against nanoparticulate intruders, while raising awareness of nanomaterials’ toxicity among scientists and manufacturers handling them.
Journal ArticleDOI
Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines.
TL;DR: It is demonstrated that only ultrafine polystyrene particles induced a significant increase in cytosolic calcium ion concentration and experiments using dichlorofluorescin diacetate demonstrated greater oxidant activity of the ultrafine particles, which may explain their activity in these assays.
Journal ArticleDOI
Combustion-derived nanoparticles: A review of their toxicology following inhalation exposure
Ken Donaldson,Lang Tran,Luis A Jimenez,Rodger Duffin,David E. Newby,Nicholas L. Mills,William MacNee,Vicki Stone +7 more
TL;DR: CDNP can be seen as a group of particulate toxins unified by a common mechanism of injury and properties of translocation which have the potential to mediate a range of adverse effects in the lungs and other organs and warrant further research.
Journal ArticleDOI
Inhaled particles and lung cancer. Part A: Mechanisms.
TL;DR: Since most of the proposed molecular mechanisms underlying particle‐related carcinogenesis have been derived from in vitro studies, there is a need for future studies that evaluate the implication of these mechanisms for in vivo lung cancer development and transgenic and gene knockout animal models may provide a useful tool.
References
More filters
Journal ArticleDOI
Chronic Inhalation Exposure of Wistar Rats and two Different Strains of Mice to Diesel Engine Exhaust, Carbon Black, and Titanium Dioxide
U. Heinrich,Rainer Fuhst,Susanne Rittinghausen,Otto Creutzenberg,Bernd Bellmann,Wolfgang Koch,Karsten Levsen +6 more
TL;DR: In this paper, Wistar rats were exposed for two years to diesel engine exhaust, carbon black (Printex 90, Degussa, FR. G), and ultraline TiO2 (P25, P25, DEG), and were subsequently kept in clean air for 6 mo.
Journal Article
Research Report No. 1
TL;DR: Freebody has agreed to contribute a research report section to each Journal in the interests of providing members with information on important developments in language and literacy education as mentioned in this paper, and this first report begins appropriately by discussing recent research into early literacy development.
Journal ArticleDOI
Comparative Pulmonary Toxicities and Carcinogenicities of Chronically Inhaled Diesel Exhaust and Carbon Black in F344 Rats
Kristen J. Nikula,Morris B. Snipes,Edward B. Barr,William C. Griffith,Rogene F. Henderson,Joe L. Mauderly +5 more
TL;DR: The results suggest that the organic fraction of DE may not play an important role in the carcinogenicity of DE in rats, and that the average dose of DE caused similar, dose-related, nonneoplastic lesions.
Pulmonary toxicity of inhaled diesel exhaust and carbon black in chronically exposed rats. Part I: Neoplastic and nonneoplastic lung lesions.
J L Mauderly,M B Snipes,E.B. Barr,S A Belinsky,James A. Bond,A.L. Brooks,I Y Chang,Yung-Sung Cheng,N A Gillett,W C Griffith +9 more
TL;DR: The pulmonary carcinogenicities and selected noncancer effects produced by chronic exposure of rats at high rates to diesel exhaust and carbon black are compared to provide insight into the likely importance of the mutagenic organic compounds associated with the soot portion of diesel exhaust in inducing pulmonary carcinogenicity in diesel exhaust-exposed rats.
Journal ArticleDOI
Vereinfachte Methode zur Messung von Oberflächengrößen durch Gasadsorption, 2. Mitteilung
R. Haul,G. Dümbgen +1 more
TL;DR: In this paper, a differential-mesverfahrens (differential mesgases als Stickstoff and Berucksichtigung des Probevolumens bei kleinen Oberflachengrosen) erortert.