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The cellular response to nerve injury. 3. The effect of repeated crush injuries.

Thomas Pk
- 01 May 1970 - 
- Vol. 106, pp 463-470
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This article is published in Journal of Anatomy.The article was published on 1970-05-01 and is currently open access. It has received 85 citations till now. The article focuses on the topics: Crush injury & Nerve injury.

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Journal ArticleDOI

The cellular and molecular basis of peripheral nerve regeneration.

TL;DR: Axonal regeneration may be facilitated by new strategies that enhance the growth potential of neurons and optimize the growth support of the distal nerve stump in combination with prompt nerve repair.
Journal ArticleDOI

Evidence that sensory axons are mitogenic for Schwann cells

TL;DR: It is reported here that the ‘bare’ sensory ganglion neurite provides a potent stimulus for thymidine incorporation and mitosis in Schwann cells.
Journal ArticleDOI

Axon outgrowth enhanced by a previous nerve injury.

TL;DR: In the sciatic nerve of adult mice, the rate of axonal elongation following nerve excision was 27% faster than normal if the nerve had been crushed two weeks before the excision.
Journal ArticleDOI

A study of degeneration and regeneration in the divided rat sciatic nerve based on electron microscopy. I. The traumatic degeneration of myelin in the proximal stump of the divided nerve.

TL;DR: In this paper, the authors examined the processes of traumatic degeneration of myelin in the proximal stump of divided rat sciatic nerves with the electron microscope, revealing a complete and coherent series of Schwann cells which are progressively more advanced in the degradation of the myelin.
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Morphometric and biochemical studies of peripheral nerves in amyotrophic lateral sclerosis

TL;DR: It is shown that in amyotrophic lateral sclerosis a small degree of dying‐back change and of distal axonal atrophy is superimposed on the degeneration of motor neuron cell bodies, and that the disease effects spread beyond the motor neurons.
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