Journal ArticleDOI
The effect of long-term intermittent trimethoprim/sulfamethoxazole treatment on recurrences of toxoplasmic retinochoroiditis.
Claudio Silveira,Rubens Belfort,Cristina Muccioli,Gary N. Holland,Cesar G. Victora,Bernardo L. Horta,Fei Yu,Robert B. Nussenblatt +7 more
TLDR
Long-term intermittent treatment with trimethoprim/sulfamethoxazole can reduce the rate of recurrent toxoplasmic retinochoroiditis.About:
This article is published in American Journal of Ophthalmology.The article was published on 2002-07-01. It has received 201 citations till now. The article focuses on the topics: Trimethoprim & Sulfamethoxazole.read more
Citations
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Toxoplasmosis in humans and animals in Brazil: high prevalence, high burden of disease, and epidemiology.
TL;DR: Prevalence, clinical spectrum, molecular epidemiology, and control of T. gondii in humans and animals in Brazil are reviewed to help biologists, public health workers, veterinarians, and physicians understand the severity of clinical toxoplasmosis in Brazilian children.
Journal ArticleDOI
Ocular toxoplasmosis: a global reassessment. Part I: epidemiology and course of disease.
TL;DR: In this paper, the authors reviewed information about prevalence of disease, sources of infection, relation of ocular disease to time of Toxoplasma gondii infection (congenital vs. postnatally acquired), and course of disease.
Monitoring of verotoxigenic Escherichia coli (VTEC) and identification of human pathogenic VTEC types 1 Scientific Opinion of the Panel on Biological Hazards
Olivier Andreoletti,Herbert Budka,Sava Buncic,Pierre Colin,John D. Collins,John W. Griffin,Arie Havelaar,James Hope,Günter Klein,Hilde Kruse,Antonio Martínez López,James McLauchlin,Christophe Nguyen-The,Birgit Noerrung,Miguel Prieto Maradona,Terence Roberts,Ivar Vågsholm,Emmanuel Vanopdenbosch +17 more
Journal ArticleDOI
Ocular toxoplasmosis: a global reassessment. Part II: disease manifestations and management.
TL;DR: The genotype of the infecting parasite appears to be an important determinant of disease severity in immunocompetent patients andVariations in disease characteristics may be related to host, parasite, or environmental factors.
Journal ArticleDOI
Treatment of Toxoplasmosis: Historical Perspective, Animal Models, and Current Clinical Practice.
Ildiko Rita Dunay,Kiran Gajurel,Reshika Dhakal,Oliver Liesenfeld,Jose G. Montoya,Jose G. Montoya +5 more
TL;DR: An overview of toxoplasmosis treatment in humans and in animal models is presented and there is a strong impetus to develop novel therapeutics for both the acute and latent forms of the infection.
References
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Journal ArticleDOI
Neonatal serologic screening and early treatment for congenital Toxoplasma gondii infection. The New England Regional Toxoplasma Working Group.
N G Guerina,Ho-Wen Hsu,H C Meissner,James H. Maguire,Ruth Lynfield,B Stechenberg,I Abroms,Mark S. Pasternack,Rodney Hoff,Roger B. Eaton +9 more
TL;DR: Routine neonatal screening for toxoplasmosis identifies congenital infections that are subclinical, and early treatment may reduce the severe long-term sequelae.
Journal ArticleDOI
An Unusually High Prevalence of Ocular Toxoplasmosis in Southern Brazil
Peter D. Glasner,Claudio Silveira,Deanna Kruszon-Moran,Maria Cristina Martins,Miguel N. Burnier,Silvia Silveira,Mario E. Camargo,Robert B. Nussenblatt,Richard A. Kaslow,Rubens Belfort +9 more
TL;DR: The prevalence of ocular toxoplasmosis in this population was more than 30 times higher than previous estimates for the same condition elsewhere and the low prevalence in the young children the authors studied supplements previous data suggesting that the disease is a sequela of postnatal rather than congenital infection.
Journal ArticleDOI
Early and Longitudinal Evaluations of Treated Infants and Children and Untreated Historical Patients with Congenital Toxoplasmosis: The Chicago Collaborative Treatment Trial
James B. McAuley,Kenneth M. Boyer,Dushyant Patel,Marilyn B. Mets,Charles N. Swisher,Nancy Roizen,Cheryl Wolters,Laszlo Stein,Mark A. Stein,William Schey,Jack S. Remington,Paul Meier,Dan L. Johnson,Peter Heydeman,Ellen Holfels,Shawn Withers,Douglas G. Mack,Charles R. Brown,Diane Patton,Rima McLeod +19 more
TL;DR: Most remarkable were the normal developmental, neurological, and ophthalmologic findings at the early follow-up evaluations of many--but not all--of the treated children despite severe manifestations, such as substantial systemic disease, hydrocephalus, microcephalus and multiple intracranial calcifications, and extensive macular destruction detected at birth.
Journal ArticleDOI
Ocular toxoplasmosis in patients with the acquired immunodeficiency syndrome
Gary N. Holland,Robert E. Engstrom,Ben J. Glasgow,Brian B. Berger,Stewart A. Daniels,Yossi Sidikaro,Janine A. Harmon,David H. Fischer,David S. Boyer,Narsing A. Rao,Ralph C. Eagle,Allan E. Kreiger,Robert Y. Foos +12 more
TL;DR: In seven of eight cases of presumed ocular toxoplasmosis in patients with AIDS, the diagnosis was supported by reduction or resolution of intraocular inflammation and healing of necrotic retinal lesions after initiation of antiparasitic drug therapy including one or more of the following medications: pyrimethamine, sulfadiazine, clindamycin, tetracycline, or spiramycin.
Journal ArticleDOI
Low-dose trimethoprim-sulfamethoxazole prophylaxis for toxoplasmic encephalitis in patients with AIDS.
Andrew Carr,Brett Tindall,Bruce J. Brew,Deborah Marriott,John Harkness,Ronald Penny,David A. Cooper +6 more
TL;DR: Low-dose trimethoprim-sulfamethoxazole (four tablets per week) appears to be effective prophylaxis against toxoplasmic encephalitis in HIV-infected patients with previous P. carinii pneumonia.