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Showing papers in "American Journal of Ophthalmology in 1996"


Journal ArticleDOI
TL;DR: For RCTs to ultimately benefit patients, the published report should be of the highest possible standard and accurate and complete reporting is needed.

1,662 citations


Journal ArticleDOI
TL;DR: In this paper, the authors used a go/no-go categorization task in which subjects have to decide whether a previously unseen photograph, flashed on for just 20 ms, contains an animal.

923 citations


Journal ArticleDOI
TL;DR: In this paper, the expression of VEGF in subfoveal fibrovascular membranes from patients with age-related macular degeneration was analyzed using in situ hybridization and immunohistochemistry.

654 citations


Journal ArticleDOI
TL;DR: Gram-positive, coagulase-negative micrococci predominated in this series andVancomycin was active against all gram-positive isolates tested and ceftazidime showed equivalent activity against gram-negative isolates.

646 citations


Journal ArticleDOI
TL;DR: The use of antibacterial sulfonamides, anticonvulsant agents, oxicam NSAIDs, allopurinol, chlormezanone, and corticosteroids is associated with large increases in the risk of Stevens-Johnson syndrome or toxic epidermal necrolysis, but for none of the drugs does the excess risk exceed five cases per million users per week.

610 citations


Journal ArticleDOI
TL;DR: In this paper, a prospective study was performed to evaluate changes in the choroidal circulation in cases of central serous chorioretinopathy, and the results indicated that capillary or venous congestion after ischemia in one or more choroid lobules might be the reason for the CHORO hyperpermeability associated with the damaged retinal pigment epithelium.

521 citations



Journal ArticleDOI
TL;DR: Although in this study the follow-up period was short and relatively few patients were studied, this approach appears to offer an alternative to keratoprosthesis for treating severe cicatricial keratoconjunctivitis with dry eye.

460 citations


Journal ArticleDOI
TL;DR: In this article, the prevalence of glaucoma among people worldwide was estimated by using available published data to determine the relation of open angle and angle closure with age in people of European, African, and Asian origin.

408 citations


Journal ArticleDOI
TL;DR: In this paper, the authors examined 213 consecutive cases of general uveitis, defined as intraocular inflammation other than cytomegalovirus retinopathy, seen by a group of community-based comprehensive ophthalmologists.

408 citations


Journal ArticleDOI
TL;DR: Colocalization of two growth factors in the same cells of ocular neovascular membranes suggests that more than one growth factor may contribute to pathologic angiogenesis and suggests that hypoxia may be an etiologic factor for choroidal as well as for retinal neov vascularization.

Journal ArticleDOI
TL;DR: Eyelid retraction is the most common clinical sign of Graves' ophthalmopathy and the complete constellation of typical features (hyperthyroidism, eyelid Retraction, exophthalmos, restrictive extraocular myopathy, and optic nerve dysfunction) occurs relatively infrequently.

Journal ArticleDOI
TL;DR: When administered orally, LY333531 ameliorated the glomerular filtration rate, albumin excretion rate, and retinal circulation in diabetic rats in a dose-responsive manner, in parallel with its inhibition of PKC activities.


Journal ArticleDOI
TL;DR: Tear lipid layer interference patterns are highly correlated with dry eye severity and there was a significant correlation between the grading and the results of other dry eye examination modalities, including fluoresceinStaining, rose bengal staining, and tear film breakup time.

Journal ArticleDOI
TL;DR: Vitrectomy effectively improved visual acuity in some eyes with diabetic macular edema associated with traction from a thickened and taut posterior hyaloid membrane.

Journal ArticleDOI
TL;DR: In eyes with diffuse diabetic macular edema and without posterior vitreous detachment, vitrectomy with posterior vitREous detachment may be effective.


Journal ArticleDOI
TL;DR: The early diagnosis of the ocular abnormalities in patients with Down's syndrome, by using Teller acuity cards in assessing visual acuity facilitates the treatment of refractive errors, strabismus, and amblyopia and may minimize handicaps.


Journal ArticleDOI
TL;DR: Data on the quantitative anatomy of the retinal pigment epithelium may be important for physiology and pathophysiology of the visual process, especially in evaluating the effects of aging.

Journal ArticleDOI
TL;DR: Treatment with co-trimoxazole reduces the incidence of relapses in patients with Wegener's granulomatosis in remission and is identified as an independent factor associated with prolonged disease-free survival and a positive antineutrophil cytoplasmic antibody test at the start of treatment as a risk factor for relapse.

Journal ArticleDOI
TL;DR: Many children with congenital toxoplasmosis have substantial retinal damage at birth and consequent loss of vision, Nonetheless, vision may be remarkably good in the presence of large macular scars.

Journal ArticleDOI
TL;DR: In this paper, intraocular fluid samples from patients with sight-threatening posterior uveitis were investigated to determine the causative agent, i.e., varicella-zoster virus or herpes simplex virus in 81% of the cases, using the combination of both techniques.

Journal ArticleDOI
TL;DR: Excimer laser in situ keratomileusis under a corneal flap can be an effective method of reducing myopia between –2.00 and –20.00 diopters, with minimal complications.

Journal ArticleDOI
TL;DR: This study supports earlier findings regarding several compliance correlates, but it identifies important new variables, such as the organizational safety climate and perceived conflict of interest, which will probably succeed in facilitating employee compliance.

Journal ArticleDOI
TL;DR: Removal of the internal limiting membrane and adherent epiretinal tissue surrounding and overlying the macular hole is a reasonable surgical approach to close idiopathic macular holes.

Journal ArticleDOI
TL;DR: This research presents a novel and scalable approach called “Neural Prosthesis Engineering for Surgical Neurology Branch” (NSPB) that addresses the challenge of directly simulating the dynamic response of the autonomic nervous system during surgery.

Journal ArticleDOI
TL;DR: Average dimensions were used to demonstrate that the number of cells and approximate growth rates vary significantly between adjacent regions, and cross-sections of fibers give new insights into the lamellar organization of the lens.

Journal ArticleDOI
TL;DR: The Nerve Fiber Analyzer may be useful for individual follow-up of people at risk for glaucoma; however, its role as a screening instrument requires further study.