Journal ArticleDOI
The effect of prolonged, reversible block of nerve impulses on the elimination of polyneuronal innervation of new-born rat skeletal muscle fibers.
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TLDR
After longer periods of block there was an increased frequency of polyneuronally innervated muscle fibers presumably due to motor nerve sprouting induced by the paralyzed muscle.About:
This article is published in Neuroscience.The article was published on 1979-02-01. It has received 224 citations till now. The article focuses on the topics: Motor nerve & Epineurium.read more
Citations
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Journal ArticleDOI
Developmental mechanisms that generate precise patterns of neuronal connectivity
Corey S. Goodman,Carla J. Shatz +1 more
TL;DR: The range of activityindependent and activity-dependent mechanisms that generate precision of neuronal connections is considered-the connections between motoneurons and muscles and between the retina and higher visual centers--to highlight the extent to which different parts of the nervous system use the same mechanisms but in different proportions to achieve the final specificity.
Journal ArticleDOI
Regressive events in neurogenesis
TL;DR: Far from being relatively minor aspects of neural development, regressive phenomena are now recognized as playing a major role in determining the form of the mature nervous system.
Journal ArticleDOI
Experience and brain development.
TL;DR: A new categorization scheme based upon the type of information stored and the brain mechanisms that appear to be involved in storing it is proposed, which offers a new view more in accord with neural mechanisms than were terms like "critical" or "sensitive period."
Journal ArticleDOI
Elimination of synapses in the developing nervous system.
Dale Purves,Jeff W. Lichtman +1 more
TL;DR: Reduction of the number of axons that contact target cells may be a general feature of neural development and underlie the progressively restricted malleability of the maturing nervous system.
OtherDOI
Motor Units: Anatomy, Physiology, and Functional Organization
TL;DR: The sections in this article are: Motor Unit Types: Histochemical Profiles and Ultrastructural Correlations, Anatomical Considerations, and Control of Muscular Action: Recruitment and Rate Modulation.
References
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Journal ArticleDOI
Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks.
TL;DR: The alternative proposed in this article is that connections are genetically specified between classes of cells, but the final wiring pattern depends on the refinement of those collections by selective stabilisation during neuronal activity.
Journal ArticleDOI
Polyneuronal innervation of skeletal muscle in new-born rats and its elimination during maturation.
TL;DR: Observations suggest that there are several factors influencing the elimination of redundant inputs in immature muscles, including individual motor neurones appear to have an inherent tendency to withdraw the majority of their original complement of peripheral terminals.
Journal ArticleDOI
Neuromuscular transmission in new‐born rats
TL;DR: End‐plate potentials (e.p.s) were recorded intracellularly from the isolated phrenic/diaphragm preparation of the rat during the first few weeks of life.
Journal Article
Anatomical changes in peripheral nerves compressed by a pneumatic tourniquet.
TL;DR: The anatomical features and distribution of this lesion suggest that the damage to the nerve fibres is a direct result of the applied pressure, and not a consequence of secondary ischaemia.
Journal ArticleDOI
Control of ACh sensitivity by muscle activity in the rat
T. Lømo,Jean Rosenthal +1 more
TL;DR: Rat soleus and extensor digitorum longus muscles were examined following complete blockade of sciatic nerve impulses with anaesthetics or diphtheria toxin for periods up to 14 days to study the effects of these treatments on musculoskeletal integrity.