Journal ArticleDOI
The effects of insulin and glucagon on the release of triacylglycerols by isolated rat hepatocytes are mere reflections of the hormonal effects on the rate of triacylglycerol synthesis
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TLDR
It is concluded that the effects of insulin and glucagon on the overall process of triacylglycerol secretion are reflections of the hormone-determined rate of Triacyl Glycerol synthesis.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1981-07-24. It has received 54 citations till now. The article focuses on the topics: Glucagon & Very low-density lipoprotein.read more
Citations
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Journal ArticleDOI
The apolipoprotein B gene is constitutively expressed in HepG2 cells: regulation of secretion by oleic acid, albumin, and insulin, and measurement of the mRNA half-life.
TL;DR: It is concluded that the apoB gene is constitutively expressed in HepG2 cells and that the mechanism of acute regulation of apiB production by these cells must involve co- or post-translational processes.
Journal ArticleDOI
Effects of Acute Hyperinsulinemia on VLDL Triglyceride and VLDL ApoB Production in Normal Weight and Obese Individuals
TL;DR: Acute hyperinsulinemia in humans suppresses plasma FFA equally in control and obese subjects at this high dose of insulin and decreases plasma triglyceride and VLDL particle size in control subjects, reflecting either stimulation of LPL activity or a greater relative decrease in triglyceride to apoB production.
Journal ArticleDOI
Nutrition during the dry period and hepatic lipid metabolism of periparturient dairy cows.
TL;DR: Cows fed the high fat diet during the dry period had decreased percentage and production of milk fat; differences among treatments were not significant for DMI, body condition, milk production, or milk protein.
Journal ArticleDOI
Effects of Insulin and Glucose on Very Low Density Lipoprotein Triglyceride Secretion by Cultured Rat Hepatocytes
TL;DR: The observed effects of insulin occurred at concentrations close to the physiological range and suggest that the direct hepatic effect is to suppress VLDL secretion although the net effect in vivo will clearly reflect many additional accompanying changes.
Journal ArticleDOI
The Role of Exogenous Insulin in the Complex of Hepatic Lipidosis and Ketosis Associated with Insulin Resistance Phenomenon in Postpartum Dairy Cattle
TL;DR: Administration of insulin with concomitant delivery of dextrose increases efficiency of treatment for hepatic lipidosis and ketosis, however, data on use of insulin to prevent these lipid-related metabolic disorders are limited and it should be investigated.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Book ChapterDOI
Preparation of isolated rat liver cells.
TL;DR: This chapter discusses preparation of isolated rat liver cells by incubation of rat liver minces with pronase, which results in most of the liver parenchyma is digested, while nonparenchymal cells remain intact and can be recovered from the incubate.
Journal ArticleDOI
Removal of Fatty Acids from Serum Albumin by Charcoal Treatment
TL;DR: Fluorescence spectra of human serum albumin samples indicated that impurities are sometimes present which can be removed by charcoal at neutral pH, and acid-charcoal treatment is a much more rapid method of removing lipid impurities than other methods previously described.
Journal ArticleDOI
Microtubule Formation in vitro in Solutions Containing Low Calcium Concentrations
TL;DR: The extreme sensitivity of tubulin to calcium ions explains the failure of previous efforts to obtain polymerization and suggests a possible mechanism for regulation of microtubule polymerization in vivo.
Journal ArticleDOI
Discoidal bilayer structure of nascent high density lipoproteins from perfused rat liver.
TL;DR: Rat livers perfused without added plasma proteins suggest that the liver secretes disk-shaped lipid bilayer particles which represent both the nascent form of high density lipoproteins and preferred substrate for lecithin-cholesterol acyltransferase.
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