The epidemiology and severity of respiratory viral infections in a tropical country: Ecuador, 2009-2016.
Saverio Caini,Doménica de Mora,Maritza Olmedo,Denisses Portugal,María A. Becerra,Marcela Mejía,María C. Pacurucu,Jenny Ojeda,Guglielmo Bonaccorsi,Chiara Lorini,John Paget,Alfredo Bruno +11 more
TLDR
The epidemiology and severity of RVI in Ecuador during 2009–2016 was compared with the timing of epidemics caused by the different viruses, with the risk of death being highest for pandemic influenza and lowest for RSV.About:
This article is published in Journal of Infection and Public Health.The article was published on 2019-05-01 and is currently open access. It has received 21 citations till now. The article focuses on the topics: Human metapneumovirus.read more
Citations
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Antiviral therapies: advances and perspectives.
Bruna Carolina Gonçalves,Mário Gabriel Lopes Barbosa,Anna Paula Silva Olak,Natalia Belebecha Terezo,Leticia Nishi,Maria Angélica Watanabe,Poliana Camila Marinello,Daniele Zendrini Rechenchoski,Sérgio Paulo Dejato da Rocha,Ligia Carla Faccin-Galhardi +9 more
TL;DR: 96 antivirals approved by the Food and Drug Administration between 1987 and 2019 are summarized and strategies are suggested as inhibitors of viral replication by various means, such as direct binding to the viral particle, blocking the infection, changes in intracellular mechanisms or viral genes, preventing replication and virion formation.
Journal ArticleDOI
Comparison of three multiplex PCR assays for detection of respiratory viruses: Anyplex II RV16, AdvanSure RV, and Real-Q RV.
Seung Gyu Yun,Seung Gyu Yun,Min Young Kim,Jong Moon Choi,Chang Kyu Lee,Chae Seung Lim,Yunjung Cho,In Bum Suh +7 more
TL;DR: The objective of this study was to perform a direct comparison of three multiplex RT‐PCR assays for the detection of respiratory viruses.
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Epidemiology of human adenovirus associated with respiratory infection in southern Brazil
Veridiane Maria Pscheidt,Tatiana Schäffer Gregianini,Letícia Garay Martins,Ana Beatriz Gorini da Veiga +3 more
TL;DR: Investigation in patients with respiratory infection in Rio Grande do Sul, Brazil, between 2004 and 2018 found that HAdV infection of the respiratory tract causes morbidity and mortality, and individuals with heart diseases and the immunocompromised are at higher risk of fatality.
Journal ArticleDOI
Epidemiology of respiratory viruses in patients with severe acute respiratory infections and influenza-like illness in Suriname.
TL;DR: Insight in viral respiratory infections in Suriname, a tropical LMIC in South America, would contribute to improved local preventive measures and a better global understanding of respiratory viruses.
References
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TL;DR: The findings show substantial progress in the reduction of lower respiratory infection burden, but this progress has not been equal across locations, has been driven by decreases in several primary risk factors, and might require more effort among elderly adults.
Journal ArticleDOI
Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory tract infections in 195 countries: a systematic analysis for the Global Burden of Disease Study 2015
Christopher Troeger,Mohammad H. Forouzanfar,Puja C Rao,Ibrahim A Khalil,Alexandria Brown,Scott J. Swartz,Nancy Fullman,Jonathan F. Mosser,Robert L. Thompson,Robert Reiner,Amanuel Alemu Abajobir,Noore Alam,Mulubirhan Assefa Alemayohu,Azmeraw T. Amare,Carl Abelardo T. Antonio,Hamid Asayesh,Euripide Frinel G Arthur Avokpaho,Aleksandra Barac,Muktar A. Beshir,Dube Jara Boneya,Michael Brauer,Lalit Dandona,Rakhi Dandona,Joseph R Fitchett,Tsegaye Tewelde Gebrehiwot,Gessessew Buggsa Hailu,Peter J. Hotez,Amir Kasaeian,Tawfik Ahmed Muthafer Khoja,Niranjan Kissoon,Luke D. Knibbs,G Anil Kumar,Rajesh Kumar Rai,Hassan Magdy Abd El Razek,Muktar Sano Kedir Mohammed,Katie Nielson,Eyal Oren,Abdalla Sidahmed Osman,George C Patton,Mostafa Qorbani,Hirbo Shore Roba,Benn Sartorius,Miloje Savic,Mika Shigematsu,Bryan L. Sykes,Soumya Swaminathan,Roman Topor-Madry,Kingsley N. Ukwaja,Andrea Werdecker,Naohiro Yonemoto,Maysaa El Sayed Zaki,Stephen S Lim,Mohsen Naghavi,Theo Vos,Simon I. Hay,Christopher J L Murray,Ali H. Mokdad +56 more
TL;DR: LRI remains a largely preventable disease and cause of death, and continued efforts to decrease indoor and ambient air pollution, improve childhood nutrition, and scale up the use of the pneumococcal conjugate vaccine in children and adults will be essential in reducing the global burden of LRI.
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Comparison of Real-Time PCR Assays with Fluorescent-Antibody Assays for Diagnosis of Respiratory Virus Infections in Children
Jane Kuypers,Nancy Wright,James Ferrenberg,Meei Li Huang,Anne Cent,Lawrence Corey,Rhoda Ashley Morrow +6 more
TL;DR: The PCR assays were significantly more sensitive than FA assays for detecting respiratory viruses, especially parainfluenza virus and adenovirus, and will lead to improved diagnosis of respiratory illness in children.
Journal ArticleDOI
Respiratory Syncytial Virus Genetic and Antigenic Diversity
TL;DR: The ability to discern intergroup and intragroup differences has increased the power of epidemiologic investigations of RSV and the differences between the two groups have led to vaccine development strategies that should provide protection against both antigenic groups.