Journal ArticleDOI
The hippocampus—what does it do?
Reads0
Chats0
About:
This article is published in Behavioral and Neural Biology.The article was published on 1992-01-01. It has received 876 citations till now. The article focuses on the topics: Amnesia & Hippocampus.read more
Citations
More filters
Journal ArticleDOI
Protective and Damaging Effects of Stress Mediators
TL;DR: The long-term effect of the physiologic response to stress is reviewed, which I refer to as allostatic load, which is the ability to achieve stability through change.
Journal ArticleDOI
Stress, adaptation, and disease. Allostasis and allostatic load.
TL;DR: The relationship of allostatic load to genetic and developmental predispositions to disease is considered and examples will be given from research pertaining to autonomic, CNS, neuroendocrine, and immune system activity.
Journal ArticleDOI
Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
TL;DR: As an adjunct to pharmaceutical therapy, social and behavioral interventions such as regular physical activity and social support reduce the chronic stress burden and benefit brain and body health and resilience.
Journal ArticleDOI
Stress and hippocampal plasticity.
TL;DR: The hippocampus is a target of stress hormones, and it is an especially plastic and vulnerable region of the brain that undergoes a selective atrophy in a number of disorders, accompanied by deficits in declarative episodic, spatial, and contextual memory performance.
Journal ArticleDOI
Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
Roussoudan Bourtchuladze,Bruno G. Frenguelli,Julie A. Blendy,Diana Cioffi,Günther Schütz,Alcino J. Silva +5 more
TL;DR: Consistent with models claiming a role for long-term potentiation (LTP) in memory, LTP in hippocampal slices from CREB mutants decayed to baseline 90 min after tetanic stimulation, however, paired-pulse facilitation and posttetanic potentiation are normal.
References
More filters
MonographDOI
Parallel Distributed Processing: Explorations in the Microstructure of Cognition: Foundations
Book
The Hippocampus as a Cognitive Map
John O'Keefe,Lynn Nadel +1 more
TL;DR: The amnesic syndrome is presented as an extension of the theory to humans and the role of operators in the locale system is examined.
Book
The Concept of Mind
TL;DR: This epoch-making book cuts through confused thinking and forces us to re-examine many cherished ideas about knowledge, imagination, consciousness and the intellect as mentioned in this paper, and the result is a classic example of philosophy.