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The Maximal Amount of Dietary α-Tocopherol Intake in U.S. Adults (NHANES 2001–2002)

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TLDR
The relations between maximal alpha-tocopherol intake and food group intakes were influenced by total fat restrictions and dramatic dietary changes that include greater intakes of nuts and seeds, and fruit and vegetables, are needed.
Abstract
The current study was designed to determine the maximal amount of alpha-tocopherol intake obtained from food in the U.S. diet, and to examine the effect of different food group intakes on this amount. Data from 2138 men and 2213 women aged >18 y were obtained from the National Health and Nutrition Examination Survey (NHANES) 2001-2002. Linear programming was used to generate diets with maximal alpha-tocopherol intake, with the conditions of meeting the recommended daily allowances or adequate intakes for a set of nutrients, sodium and fat recommendations, and energy limits, and that were compatible with the observed dietary patterns in the population. With food use and energy constraints in models, diets formulated by linear programming provided 19.3-24.9 mg alpha-tocopherol for men and women aged 19-50 or >50 y. These amounts decreased to 15.4-19.9 mg with the addition of the sodium, dietary reference intake, and fat constraints. The relations between maximal alpha-tocopherol intake and food group intakes were influenced by total fat restrictions. Although meeting current recommendations (15 mg/d) appears feasible for individuals, dramatic dietary changes that include greater intakes of nuts and seeds, and fruit and vegetables, are needed. Careful selection of the highest vitamin E source foods within these groups could further increase the likelihood of meeting the current recommended daily allowance.

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Prospective study of dietary pattern and risk of Parkinson

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The Boston Puerto Rican Health Study, a longitudinal cohort study on health disparities in Puerto Rican adults: challenges and opportunities.

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References
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Journal ArticleDOI

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

TL;DR: No reduction in the incidence of lung cancer among male smokers is found after five to eight years of dietary supplementation with alpha-tocopherol or beta carotene, and this trial raises the possibility that these supplements may actually have harmful as well as beneficial effects.
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Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality

TL;DR: This meta-analysis of 19 randomized, controlled trials involving more than 135000 participants found that high-dosage vitamin E supplementation (400 IU/d for at least 1 year) increased all-cause mortality.
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Vitamin E consumption and the risk of coronary disease in women.

TL;DR: As compared with women in the lowest fifth of the cohort with respect to vitamin E intake, those in the top fifth had a relative risk of major coronary disease of 0.66, after adjustment for age and smoking.
Journal ArticleDOI

Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.

TL;DR: In patients with vascular disease or diabetes mellitus, long-term vitamin E supplementation does not prevent cancer or major cardiovascular events and may increase the risk for heart failure.
Journal ArticleDOI

Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer The Women's Health Study: A Randomized Controlled Trial

TL;DR: The data from this large trial indicated that 600 IU of natural-source vitamin E taken every other day provided no overall benefit for major cardiovascular events or cancer, did not affect total mortality, and decreased cardiovascular mortality in healthy women.
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