Journal ArticleDOI
The mechanism of the hydrolysis of N-aryl-D-glucosylamines.
Brain Capon,Brian E. Connett +1 more
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This article is published in Journal of The Chemical Society-perkin Transactions 1.The article was published on 1965-01-01. It has received 26 citations till now. The article focuses on the topics: Hydrolysis constant & Enzymatic hydrolysis.read more
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Nucleophilic catalysis of carbohydrate oxime formation by anilines.
Mikkel B. Thygesen,Henrik K. Munch,Jørgen Sauer,Emiliano Cló,Joergensen Malene Ryborg,Ole Hindsgaul,Knud J. Jensen +6 more
TL;DR: It is presented that carbohydrate oxime formation can be catalyzed with up to 20-fold increases in overall reaction rate at 100 mM aniline, and application of this methodology provided access to complex glycoconjugates.
Journal ArticleDOI
Kinetic study of the reaction of sulfamethoxazole and glucose under acidic conditions: I. Effect of pH and temperature.
TL;DR: In this paper, the authors investigated the kinetics of the reaction of sulfamethoxazole (SMX) in 5% w/v glucose to form the corresponding alpha- and beta-glucosylamines over the pH range of 0.80-2.88 at 37 degrees C.
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Chemical Structure and Properties of Interstrand Cross-Links Formed by Reaction of Guanine Residues with Abasic Sites in Duplex DNA
Michael J. Catalano,Shuo Liu,Nisana Andersen,Zhiyu Yang,Kevin M. Johnson,Nathan E. Price,Yinsheng Wang,Kent S. Gates +7 more
TL;DR: The results establish the chemical connectivity of the dG-AP cross-link released from duplex DNA and provide a foundation for detection of this lesion in biological samples, suggesting it may have the power to block DNA-processing enzymes involved in transcription and replication.
Journal ArticleDOI
Glycosylation of human hemoglobin A. Kinetics and mechanisms studied by isoelectric focusing.
TL;DR: The reaction between glucose and hemoglobin A (HbA) leading to hemoglobins A1c through a labile intermediate, designated anodal glycohemoglobin A, was studied in vitro using an isoelectric focusing method and the equilibrium constant K is predicted to be nearly temperature-independent within the temperature range investigated.
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Is there a generalized reverse anomeric Effect? substituent and solvent effects on the configurational equilibria of neutral and protonated N-arylglucopyranosylamines and N-aryl-5-thioglucopyranosylamines
TL;DR: The changes in the values of the C(1)-H(1) coupling constants for 1-4 and the corresponding deacetylated compounds 5-8 as a function of substituent and alpha- or beta-configuration are discussed in terms of the Perlin effect and the interplay of the endo- and exo-anomeric effects.
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Kinetik der Hydrolyse von Benzalanilin II: Die pH‐Abhängigkeit der Reaktionsgeschwindigkeit in ungepufferten Lösungen und die Rolle der Aminoalkohol‐Zwischenstufe
TL;DR: In this paper, the hydrolyses of benzalaniline and some of its derivatives have been investigated in unbuffered solutions (50:50 methanol-water with 0,110-n. KC1) at 20°.
Journal ArticleDOI
A kinetic study of the hydrolysis of benzalaniline
A. V. Willi,R. E. Robertson +1 more
TL;DR: In this paper, the rates of acid catalyzed hydrolysis of a series of para substituted benzalanilines have been studied in 50/50 methanol-water in the presence of acetate buffers.