scispace - formally typeset
Journal ArticleDOI

The mismatch negativity (MMN) - A unique window to disturbed central auditory processing in ageing and different clinical conditions

Reads0
Chats0
TLDR
It was found that in a large number of different neuropsychiatric, neurological and neurodevelopmental disorders, as well as in normal ageing, the MMN amplitude was attenuated and peak latency prolonged and appears to index cognitive decline irrespective of the specific symptomatologies and aetiologies of the different disorders involved.
About
This article is published in Clinical Neurophysiology.The article was published on 2012-03-01. It has received 346 citations till now. The article focuses on the topics: Mismatch negativity & Cognitive decline.

read more

Citations
More filters
Journal ArticleDOI

Issues and considerations for using the scalp surface Laplacian in EEG/ERP research: A tutorial review.

TL;DR: Common reservations against the universal use of the surface Laplacian are reviewed and argued from a pragmatic perspective that not only are these reservations unfounded but that the continued predominant use of surface potentials poses a considerable impediment on the progress of EEG and ERP research.
Journal ArticleDOI

The mismatch-negativity (MMN) component of the auditory event-related potential to violations of abstract regularities: a review.

TL;DR: Neural, behavioral and cognitive events associated with the development of the regularity representations are discussed and it is revealed that the central auditory system performs even at the pre-attentive, auditory-cortex level surprisingly "cognitive" operations, such as generalization leading to simple concept formation, rule extraction and prediction of future stimuli.
Journal ArticleDOI

Mismatch Negativity (MMN) as an Index of Cognitive Dysfunction

TL;DR: This general finding suggests that while not serving as a specific marker to any particular disorder, MMN may be useful for understanding factors of cognition in various disorders, and has potential to serve as an indicator of risk.
Journal ArticleDOI

MMN and novelty P3 in coma and other altered states of consciousness: a review.

TL;DR: How passive auditory oddball paradigms including deviant and novel sounds have proved their efficiency in assessing brain function at a higher level, without requiring the patient’s active involvement, is reviewed, thus providing an enhanced tool for the prediction of coma outcome.
Journal ArticleDOI

The Neuronal Basis of Predictive Coding Along the Auditory Pathway: From the Subcortical Roots to Cortical Deviance Detection.

TL;DR: There is enough empirical evidence to consider SSA and MMN, respectively, as the microscopic and macroscopic manifestations of the same physiological mechanism of deviance detection in the auditory cortex, and the development of a common theoretical framework is all the more recommendable for future studies.
References
More filters
Journal ArticleDOI

The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions

TL;DR: The authors discuss the etymology and strategy behind the use of endophenotypes in neuropsychiatric research and, more generally, in research on other diseases with complex genetics.
Journal ArticleDOI

Negative affectivity: The disposition to experience aversive emotional states

TL;DR: A number of apparently diverse personality scales—variously called trait anxiety, neuroticism, ego strength, general maladjustment, repression-sensitization, and social desirability—are reviewed and are shown to be in fact measures of the same stable and pervasive trait.
Journal ArticleDOI

Magnetoencephalography—theory, instrumentation, and applications to noninvasive studies of the working human brain

TL;DR: The mathematical theory of the method is explained in detail, followed by a thorough description of MEG instrumentation, data analysis, and practical construction of multi-SQUID devices.
Journal ArticleDOI

Excitatory amino acids as a final common pathway for neurologic disorders.

TL;DR: In many neurologic disorders, injury to neurons may be caused at least in part by overstimulation of receptors for excitatory amino acids, including glutamate and aspartate.
Journal ArticleDOI

Early selective-attention effect on evoked potential reinterpreted ☆

TL;DR: The ‘Hillyard effect’ was explained as being caused by a superimposition of a CNV kind of negative shift on the evoked potential to the attended stimuli rather than by a growth of the ‘real’ N 1 component of theevoked potential.
Related Papers (5)