Open AccessJournal Article
The placental transfer of IgG subclasses in human pregnancy.
TLDR
It was found that there was a close linear relationship between gestational age and the placental transfer of IgG and each of its subclasses.Abstract:
Total IgG concentrations and the concentrations of the four subclasses of IgG were estimated in thirty-four pairs of maternal and foetal sera from pregnancies of various gestations ranging from 28 to 42 weeks using the method of radial immunodiffusion. It was found that: (1) all subclasses of IgG cross the human placenta freely, (2) foetal levels of IgG and each subclass of IgG exceed maternal levels in full-term pregnancies and (3) there was a close linear relationship between gestational age and the placental transfer of IgG and each of its subclasses.read more
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Placental transport of immunoglobulin G.
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Placental transport of immunoglobulins: a clinical review for gastroenterologists who prescribe therapeutic monoclonal antibodies to women during conception and pregnancy.
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