The Protective Effect of Moderate Alcohol Consumption on Ischemic Stroke
Ralph L. Sacco,Mitchell S.V. Elkind,Bernadette Boden-Albala,I-Feng Lin,D. E. Kargman,W. A. Hauser,Steven Shea,Myunghee Cho Paik +7 more
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TLDR
Moderate alcohol consumption was independently associated with a decreased risk of ischemic stroke in the elderly, multiethnic, urban subjects, while heavy alcohol consumption had deleterious effects.Abstract:
ContextModerate alcohol consumption has been shown to be
protective for coronary heart disease, but the relationship between
moderate alcohol consumption and ischemic stroke is more controversial.ObjectiveTo determine the association between alcohol
consumption and risk of ischemic stroke.DesignPopulation-based case-control study conducted between July
1993 and June 1997.SettingMultiethnic population in northern Manhattan, New York,
NY, aged 40 years or older.Patients and Other ParticipantsCases (n=677) had first
ischemic stroke and were matched to community controls (n=1139)
derived through random digit dialing by age, sex, and race/ethnicity.
Mean ± SD age of cases was 70.0 ± 12.7 years; 55.8% were women;
19.5% were white, 28.4% black, and 50.7% Hispanic.Main Outcome MeasureFirst ischemic stroke (fatal or nonfatal).ResultsModerate alcohol consumption, up to 2 drinks per day, was
significantly protective for ischemic stroke after adjustment for
cardiac disease, hypertension, diabetes, current smoking, body mass
index, and education (odds ratio [OR], 0.51; 95% confidence interval
[CI], 0.39-0.67). This protective effect of alcohol consumption was
detected in both younger and older groups, in men and women, and in
whites, blacks, and Hispanics. In a quadratic model of stroke risk,
increased risk of ischemic stroke was statistically significant among
those consuming 7 or more drinks per day (OR, 2.96; 95% CI,
1.05-8.29).ConclusionsModerate alcohol consumption was independently
associated with a decreased risk of ischemic stroke in our elderly,
multiethnic, urban subjects, while heavy alcohol consumption had
deleterious effects. Our data support the National Stroke Association
Stroke Prevention Guidelines regarding the beneficial effects of
moderate alcohol consumption.read more
Citations
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Guidelines for the prevention of stroke in patients with stroke and transient ischemic attack: a guideline for healthcare professionals from the American Heart Association/American Stroke Association
Walter N. Kernan,Bruce Ovbiagele,Henry R. Black,Dawn M. Bravata,Marc I. Chimowitz,Michael D. Ezekowitz,Margaret C. Fang,Marc Fisher,Karen L. Furie,Donald V. Heck,S. Claiborne Johnston,Scott E. Kasner,Steven J. Kittner,Pamela H. Mitchell,Michael W. Rich,DeJuran Richardson,Lee H. Schwamm,John A. Wilson +17 more
TL;DR: In this paper, the authors provided evidence-based recommendations for the prevention of future stroke among survivors of ischemic stroke or transient ischemi-chemic attack, including the control of risk factors, intervention for vascular obstruction, antithrombotic therapy for cardioembolism, and antiplatelet therapy for noncardioembolic stroke.
Journal ArticleDOI
Guidelines for the Primary Prevention of Stroke A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
Larry B. Goldstein,Cheryl Bushnell,Robert J. Adams,Lawrence J. Appel,Lynne T. Braun,Seemant Chaturvedi,Mark A. Creager,Antonio Culebras,Robert H. Eckel,Robert G. Hart,Judith A. Hinchey,Virginia J. Howard,Edward C. Jauch,Steven R. Levine,James F. Meschia,Wesley S. Moore,J.V. (Ian) Nixon,Thomas A. Pearson +17 more
TL;DR: Evidence-based recommendations are included for the control of risk factors, interventional approaches to atherosclerotic disease of the cervicocephalic circulation, and antithrombotic treatments for preventing thrombosis and thromboembolic stroke.
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Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer
Penny M. Kris-Etherton,Kari D Hecker,Andrea Bonanome,Stacie M. Coval,Amy E. Binkoski,Kirsten F Hilpert,Amy E. Griel,Terry D. Etherton +7 more
TL;DR: Many bioactive compounds are extranutritional constituents that typically occur in small quantities in foods and are grouped accordingly as phenolic compounds, including their subcategory, flavonoids as discussed by the authors.
Journal ArticleDOI
Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic Attack : A statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke : Co-sponsored by the Council on Cardiovascular Radiology and Intervention : The American Academy of Neurology affirms the value of this guideline
Ralph L. Sacco,Robert J. Adams,Greg Albers,Mark J. Alberts,Oscar R. Benavente,Karen L. Furie,Larry B. Goldstein,Philip B. Gorelick,Jonathan L. Halperin,Robert E. Harbaugh,S. Claiborne Johnston,Irene L. Katzan,Margaret Kelly-Hayes,Edgar J. Kenton,Michael P. Marks,Lee H. Schwamm,Thomas A. Tomsick +16 more
TL;DR: In this paper, the authors provide comprehensive and timely evidence-based recommendations on the prevention of ischemic stroke among survivors of stroke or transient ischemi stroke, including the control of risk factors, interventional approaches for atherosclerotic disease, antithrombotic treatments for cardioembolism, and the use of antiplatelet agents for noncardioembolic stroke.
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Primary prevention of coronary heart disease in women through diet and lifestyle.
TL;DR: Among women, adherence to lifestyle guidelines involving diet, exercise, and abstinence from smoking is associated with a very low risk of coronary heart disease.
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