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Journal ArticleDOI

The role of fatty acid binding protein on the metabolism of fatty acids in isolated rat hepatocytes.

TLDR
The results indicate that the cytosol fatty-acid-binding protein directs the metabolism of long chain fatty acids toward esterification as well as enhancing their cellular uptake.
About
This article is published in Biochemical and Biophysical Research Communications.The article was published on 1976-08-09. It has received 69 citations till now. The article focuses on the topics: Fatty acid & Oleic acid.

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Journal ArticleDOI

Carnitine--metabolism and functions

J. Bremer
TL;DR: The only firmly established function of carnitine is its function as a carrier of activated fatty acids and activated acetate across the inner mitochondrial membrane, and the regulation of its synthesis is still incompletely understood.
Journal ArticleDOI

Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling.

TL;DR: The observations that the ryanodine-senstitive Ca2+-release channel is regulated by long-chain acyl-CoA esters in the presence of a molar excess of acyl -CoA binding protein and that acetyl- coA carboxylase, the AMP kinase kinase and the Escherichia coli transcription factor FadR are affected by low nanomolar concentrations of Acyl- CoA indicate that long- chain acyl
Journal ArticleDOI

The fatty acid transport function of fatty acid-binding proteins.

TL;DR: Data from a number of experimental approaches have provided strong support for defining the FABPs as fatty acid transport proteins, and further studies are necessary to elucidate the fundamental mechanisms by which cellular fatty acid trafficking is modulated by theFABPs.
Book ChapterDOI

The cellular fatty acid binding proteins: aspects of structure, regulation, and function.

TL;DR: This chapter provides a comprehensive overview of the current state of knowledge of the research with particular emphasis on evolving concepts of fatty acid binding proteins (FABP) structure, regulation, and function.
Journal ArticleDOI

Regulation of the biosynthesis of two distinct fatty acid-binding proteins in rat liver and intestine. Influences of sex difference and of clofibrate.

TL;DR: The results indicate that the influence of sex difference and the effect of clofibrate on hepatic fatty acid metabolism are both associated with changes in hFABP synthesis mediated pretranslationally.
References
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Journal ArticleDOI

A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter

TL;DR: A modification of the naphthalene-dioxane-PPO liquid scintillator has been described which will allow up to 3.0 ml of an aqueous solution to be counted as mentioned in this paper.
Journal ArticleDOI

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS: A Biochemical and Fine Structural Study

TL;DR: Cytoplasmic vacuolization in a small percentage of cells and potassium loss are the only indications of cell injury detected, and the isolated cells are comparable to normal hepatic parenchymal cells in situ in appearance and function.
Journal ArticleDOI

A binding protein for fatty acids in cytosol of intestinal mucosa, liver, myocardium, and other tissues.

TL;DR: A protein of molecular weight ∼ 12,000 which binds long-chain fatty acids and certain other lipids has been identified in cytosol of intestinal mucosa, liver, myocardium, adipose tissue, and kidney and appears to be identical with the smaller of two previously described cytoplasmic anion-binding proteins.
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