The role of noradrenaline in tuning and dopamine in switching between signals in the CNS.
Robert D. Oades,Robert D. Oades +1 more
TLDR
It is suggested that the tuning principle in noradrenergic systems is particularly important for the formation of associations and neural plasticity (interference control) and that the switching principle of dopaminergic systems modulates the timing, time-sharing and initiation of responses (program-control).About:
This article is published in Neuroscience & Biobehavioral Reviews.The article was published on 1985-06-01 and is currently open access. It has received 302 citations till now. The article focuses on the topics: Dopaminergic.read more
Citations
More filters
Journal ArticleDOI
Conflict monitoring and cognitive control.
TL;DR: Two computational modeling studies are reported, serving to articulate the conflict monitoring hypothesis and examine its implications, including a feedback loop connecting conflict monitoring to cognitive control, and a number of important behavioral phenomena.
Journal ArticleDOI
A neuropsychological theory of positive affect and its influence on cognition.
TL;DR: A new neuropsychological theory is proposed that accounts for many of the effects of positive affect on olfaction, the consolidation of long-term memories, working memory, and creative problem solving by assuming that positive affect is associated with increased brain dopamine levels.
Journal ArticleDOI
The principal features and mechanisms of dopamine modulation in the prefrontal cortex
TL;DR: Certain principles of DA mechanisms are identified by drawing on published, as well as unpublished data from PFC and other CNS sites to shed light on aspects of DA neuromodulation and address some of the existing controversies.
Journal ArticleDOI
The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking
Satoshi Ikemoto,Jaak Panksepp +1 more
TL;DR: The present analysis suggests that NAS DA plays an important role in sensorimotor integrations that facilitate flexible approach responses, and offers the following interpretation for the finding that both conditioned and unconditioned aversive stimuli stimulate DA release in the NAS: NAS DA invigorates approach responses toward 'safety'.
Journal ArticleDOI
The neuropsychology of schizophrenia.
TL;DR: A model is proposed for integrating the neural and cognitive aspects of the positive symptoms of acute schizophrenia, using evidence from postmortem neuropathology and neurochemistry, clinical and preclinical studies of dopaminergic neurotransmission, anatomical connections between the limbic system and basal ganglia, attentional and other cognitive abnormalities underlying the positive Symptoms of schizophrenia.
References
More filters
Journal Article
Evidence for the existence of monoamine-containing neurons in the central nervous system. i. demonstration of monoamines in the cell bodies of brain stem neurons.
Dahlstroem A,Fuxe K +1 more
Journal ArticleDOI
Précis of The Neuropsychology of Anxiety: An Enquiry into the Functions of the Septo-Hippocampal System..
TL;DR: It is proposed that these drugs reduce anxiety by impairing the functioning of a widespread neural system including the septo-hippocampal system (SHS), the Papez circuit, the prefrontal cortex, and ascending monoaminergic and cholinergic pathways which innervate these forebrain structures.
Journal ArticleDOI
A Theory of Attention: Variations in the Associability of Stimuli with Reinforcement
TL;DR: Overshadowing and blocking are better explained by the choice of an appropriate rule for changing a, such that a decreases to stimuli that signal no change from the probability of reinforcement predicted by other stimuli.
Journal ArticleDOI
A cortical network for directed attention and unilateral neglect.
TL;DR: A network approach to the localization of complex functions offers an alternative to more extreme approaches, some of which stress an exclusive concentration of function within individual centers in the brain and others which advocate a more uniform (equipotential or holistic) distribution.