Journal ArticleDOI
Tricuspid annular plane systolic excursion and pulmonary arterial systolic pressure relationship in heart failure: an index of right ventricular contractile function and prognosis
Marco Guazzi,Francesco Bandera,Gabriele Pelissero,Serenella Castelvecchio,Lorenzo Menicanti,Stefano Ghio,Pierluigi Temporelli,Ross Arena +7 more
TLDR
This study shows that the TAPSE vs. PASP relationship is shifted downward in nonsurvivors with a similar distribution in HFrEF and HFpEF, and their ratio improves prognostic resolution.Abstract:
Echo-derived pulmonary arterial systolic pressure (PASP) and right ventricular (RV) tricuspid annular plane systolic excursion (TAPSE; from the end of diastole to end-systole) are of basic relevanc...read more
Citations
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Journal ArticleDOI
Evaluation and Management of Right-Sided Heart Failure: A Scientific Statement From the American Heart Association.
Marvin A. Konstam,Michael S. Kiernan,Daniel Bernstein,Biykem Bozkurt,Miriam Jacob,Navin K. Kapur,Robb D. Kociol,Eldrin F. Lewis,Mandeep R. Mehra,Francis D. Pagani,Amish N. Raval,Carey Ward +11 more
TL;DR: RHF is a complex syndrome including diverse causes, pathways, and pathological processes and multiple hemodynamic and biochemical markers are associated with worsening RHF and can serve to guide clinical assessment and therapeutic decision making.
Journal ArticleDOI
Right heart dysfunction in heart failure with preserved ejection fraction
TL;DR: Right heart dysfunction is common in HFpEF and is caused by both RV contractile impairment and afterload mismatch from pulmonary hypertension, and may represent a novel therapeutic target.
Journal ArticleDOI
RV Contractile Function and its Coupling to Pulmonary Circulation in Heart Failure With Preserved Ejection Fraction : Stratification of Clinical Phenotypes and Outcomes
Marco Guazzi,Debra Dixon,Valentina Labate,Lauren Beussink-Nelson,Francesco Bandera,Michael J. Cuttica,S.J. Shah +6 more
TL;DR: A thorough assessment of RV-PC coupling and RV contractile function stratify HFpEF phenotypes at different level of risk revealed the TAPSE/PASP ratio emerged as an independent predictor of worse outcomes.
Journal ArticleDOI
Pulmonary Hypertension in Heart Failure: Pathophysiology, Pathobiology, and Emerging Clinical Perspectives.
Marco Guazzi,Robert Naeije +1 more
TL;DR: Attention is focused on establishing a definitive consensus for a hemodynamic definition, perhaps incorporating exercise and fluid challenge, and searching for effective therapies that may benefit lung vessels and the remodeled right ventricle.
Journal ArticleDOI
Right heart dysfunction and failure in heart failure with preserved ejection fraction: mechanisms and management. Position statement on behalf of the Heart Failure Association of the European Society of Cardiology.
Thomas M. Gorter,Dirk J. van Veldhuisen,Johann Bauersachs,Barry A. Borlaug,Jelena Celutkiene,Andrew J.S. Coats,Andrew J.S. Coats,Marisa G. Crespo-Leiro,Marco Guazzi,Veli-Pekka Harjola,Stephane Heymans,Loreena Hill,Mitja Lainscak,Carolyn S.P. Lam,Lars H. Lund,Alexander R. Lyon,Alexandre Mebazaa,Christian Mueller,Walter Paulus,Burkert Pieske,Massimo F. Piepoli,Frank Ruschitzka,Frans H. Rutten,Petar M. Seferović,Scott D. Solomon,Sanjiv J. Shah,Filippos Triposkiadis,Rolf Wachter,Carsten Tschöpe,Rudolf A. de Boer +29 more
TL;DR: In this paper, the authors reviewed the prevalence, diagnosis, and pathophysiology of right heart dysfunction and failure in patients with heart failure with preserved ejection fraction (HFpEF) and discussed potential treatment strategies, important knowledge gaps and future directions regarding the right side in HFpEF.
References
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Journal ArticleDOI
Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography Endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography
Lawrence G. Rudski,Wyman W. Lai,Jonathan Afilalo,Lanqi Hua,Mark D. Handschumacher,Krishnaswamy Chandrasekaran,Scott D. Solomon,Eric K. Louie,Nelson B. Schiller +8 more
TL;DR: The Society of Echocardiography (SEDC) is an educational activity for cardiovascular physicians and cardiac sonographers with a knowledge base in the field of echo-cardiography as discussed by the authors.
Journal ArticleDOI
Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography
Lawrence G. Rudski,Wyman W. Lai,Jonathan Afilalo,Lanqi Hua,Mark D. Handschumacher,Krishnaswamy Chandrasekaran,Scott D. Solomon,Eric K. Louie,Nelson B. Schiller +8 more
TL;DR: This activity is designed for all cardiovascular physicians and cardiac sonographers with arest and knowledge base in the field of echocardiography and reschers, clinicians, intensivists, and other medical professionals with a spein cardiac ultrasound will find this activity beneficial.
Journal ArticleDOI
Independent and additive prognostic value of right ventricular systolic function and pulmonary artery pressure in patients with chronic heart failure
Stefano Ghio,Antonello Gavazzi,Carlo Campana,C. Inserra,Catherine Klersy,R. Sebastiani,Eloisa Arbustini,Recusani F,Luigi Tavazzi +8 more
TL;DR: It was found that RVEF was preserved in some patients with pulmonary hypertension, and that the prognosis of these patients was similar to that of the patients with normal PAP, which emphasize the necessity of combining the right heart hemodynamic variables with a functional evaluation of the RV when trying to define the individual risk of patients with heart failure.
Journal ArticleDOI
Pulmonary Hypertension in Heart Failure With Preserved Ejection Fraction: A Community-Based Study
Carolyn S.P. Lam,Véronique L. Roger,Richard J. Rodeheffer,Barry A. Borlaug,Felicity Enders,Margaret M. Redfield +5 more
TL;DR: Although pulmonary venous HTN contributes to PH, it does not fully account for the severity of PH in HFpEF, suggesting that a component of pulmonary arterial HTN also contributes.
Journal ArticleDOI
Tricuspid annular displacement predicts survival in pulmonary hypertension.
Paul R. Forfia,Micah R. Fisher,Stephen C. Mathai,Traci Housten-Harris,Anna R. Hemnes,Barry A. Borlaug,Elzbieta Chamera,Mary C. Corretti,Hunter C. Champion,Theodore P. Abraham,Reda E. Girgis,Paul M. Hassoun +11 more
TL;DR: TAPSE powerfully reflects RV function and prognosis in PAH and persisted after adjusting for other echocardiographic and hemodynamic variables and baseline treatment status.
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