Trypanosoma evansi: cholinesterase activity in acutely infected Wistar rats.
Patrícia Wolkmer,Sonia Terezinha dos Anjos Lopes,Carina Franciscato,Aleksandro Schafer da Silva,Carolina Kist Traesel,Lucas Carvalho Siqueira,Maria Ester Pereira,Silvia Gonzalez Monteiro,Cinthia M. Mazzanti +8 more
TLDR
Reductions in the activity of cholinesterase occur in acute infection by T. evansi in rats and this demonstrates an important change occurring in animals infected by the protozoan and may indicate a potential role the enzymes play in the mechanism of disease.About:
This article is published in Experimental Parasitology.The article was published on 2010-07-01 and is currently open access. It has received 23 citations till now. The article focuses on the topics: Trypanosoma evansi & Cholinesterase.read more
Citations
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Journal ArticleDOI
Acetylcholinesterase activity and lipid peroxidation in the brain and spinal cord of rats infected with Trypanosoma evansi
Aleksandro Schafer da Silva,Silvia Gonzalez Monteiro,Jamile F. Gonçalves,Roselia Maria Spanevello,Camila B. Oliveira,Márcio Machado Costa,Jeandre Augusto dos Santos Jaques,Vera Maria Morsch,Maria Rosa Chitolina Schetinger,Maria Rosa Chitolina Schetinger,Cinthia M. Mazzanti,Sonia Terezinha dos Anjos Lopes +11 more
TL;DR: It is concluded that the changes in AChE activity and lipid peroxidation in the CNS are induced by infection with T. evansi, suggesting that the parasite interferes with the cholinergic neurotransmission in this experimental condition.
Journal ArticleDOI
Pre-treatment with curcumin modulates acetylcholinesterase activity and proinflammatory cytokines in rats infected with Trypanosoma evansi
Patrícia Wolkmer,Cássia B. da Silva,Francine C. Paim,Marta M.M.F. Duarte,Verônica Souza Paiva Castro,Heloisa Einloft Palma,Raqueli T. França,Diandra Visentini Felin,Lucas Carvalho Siqueira,Sonia Terezinha dos Anjos Lopes,Maria Rosa Chitolina Schetinger,Silvia Gonzalez Monteiro,Cinthia M. Mazzanti +12 more
TL;DR: It is found that Cur is not so important as an antitrypanosomal activity but as immunomodulator agent, and preventive use of Cur stimulates anti-inflammatory mechanisms, reducing an excessive inflammatory response.
Journal ArticleDOI
Evaluation of oxidative stress and antioxidant status, serum trace mineral levels and cholinesterases activity in cattle infected with Anaplasma marginale.
Bijan Esmaeilnejad,Mousa Tavassoli,Awat Samiei,Nasser Hajipour,Abbas Imani-Baran,Farhad Farhang-Pajuh +5 more
TL;DR: The significant decrease in antioxidant enzyme activities and substantial elevated levels of lipid peroxidation and erythrocyte osmotic fragility associated with the notable increase in parasitemia indicate increased exposure of RBCs to oxidative damage.
Journal ArticleDOI
Serum Total Cholinesterase Activity on Admission Is Associated with Disease Severity and Outcome in Patients with Traumatic Brain Injury.
Qing-Hong Zhang,An-Min Li,Sai-Lin He,Xu-Dong Yao,Jing Zhu,Zhi-Wen Zhang,Zhi-yong Sheng,Yong-ming Yao +7 more
TL;DR: Lowered ChE activity measured on admission appears to be associated with disease severity and outcome for TBI patients and was identified as a borderline independent predictor for mortality.
Journal ArticleDOI
Trypanosoma evansi: Immune response and acetylcholinesterase activity in lymphocytes from infected rats
Aleksandro Schafer da Silva,Silvia Gonzalez Monteiro,Jamile F. Gonçalves,Roselia Maria Spanevello,Roberta Schmatz,Camila B. Oliveira,Márcio Machado Costa,Raqueli T. França,Jeandre Augusto dos Santos Jaques,Maria Rosa Chitolina Schetinger,Maria Rosa Chitolina Schetinger,Cinthia M. Mazzanti,Sonia Terezinha dos Anjos Lopes +12 more
TL;DR: The infection by T. evansi influences AChE activity in lymphocytes of rats indicating changes in the responses of cholinergic system in acute phase, possibly due to immune functions performed by these enzymes.
References
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Journal ArticleDOI
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
TL;DR: This assay is very reproducible and rapid with the dye binding process virtually complete in approximately 2 min with good color stability for 1 hr with little or no interference from cations such as sodium or potassium nor from carbohydrates such as sucrose.
Journal ArticleDOI
A new and rapid colorimetric determination of acetylcholinesterase activity.
TL;DR: A photometric method for determining acetylcholinesterase activity of tissue extracts, homogenates, cell suspensions, etc., has been described and Kinetic constants determined by this system for erythrocyte eholinesterases are presented.
Book
Schalm's Veterinary Hematology
TL;DR: Section I - Essential Hematologic Concepts Section II - Hemopoiesis Section III - The Erythrocytes Section IV -Leukocytes - Lymphocytes Section V - Leukocyte - Nonlymphoid Leukocytes Section VI - Hemostasis: Platelets - Platelet Structure and Function.
Journal ArticleDOI
Acetylcholinesterase New roles for an old actor
Hermona Soreq,Shlomo Seidman +1 more
TL;DR: The time is ripe to summarize the evidence on a remarkable diversity of acetylcholinesterase functions, as well as some of the long-suspected 'non-classical' actions of this enzyme, which have more recently driven a profound revolution in research.
Journal ArticleDOI
Neurobiology of butyrylcholinesterase.
TL;DR: Evidence that butyrylcholinesterase has important roles in cholinergic neurotransmission and could be involved in other nervous system functions and in neurodegenerative diseases is reviewed.