Journal ArticleDOI
Über die absolute Konfiguration des Morphins und verwandter Alkaloide
TLDR
Thebaine (VII) has been degraded to (−)-cis-[2-methyl-2-carboxy-cyclohexyl-(1)]-acetic acid (III), thus providing experimental proof of the absolute configuration of morphine, thebaine and related alkaloids as discussed by the authors.Abstract:
Thebaine (VII) has been degraded to (−)-cis-[2-methyl-2-carboxy-cyclohexyl-(1)]-acetic acid (III), thus providing experimental proof of the absolute configuration of morphine, thebaine and related alkaloids.read more
Citations
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Journal ArticleDOI
Stereochemical Factors and Receptor Interactions Associated with Narcotic Analgesics
Journal ArticleDOI
The Chemical History of Morphine: An 8000-year Journey, from Resin to de-novo Synthesis.
TL;DR: This study contrasts the cumulative scientific discoveries that have led to the current chemical knowledge of morphine with the centuries-old natural method of morphine production that still dominates the opioid market today.
Book ChapterDOI
Dopamine agonists: structure-activity relationships
TL;DR: This review surveys classes of structures for which putative dopaminergic agonism has been reported, and cites structure-activity correlations, and some aspects of metabolism of the agents are addressed, which seem to have relevance to structure- activity considerations and to strategy of drug design.
References
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Journal ArticleDOI
Veratrum‐Alkaloide. 2. Mitteilung. Über die Konstitution der Hexan‐tetracarbonsäure aus Cevin und Germin
TL;DR: In this article, the IR-Absorptionsspektrum der synthetischen racemischen Verbindung in Chloroform is identisch with demjenigen des rechtsdrehenden Keton-anhydrids C9H10O4, das aus der Hexan-tetracarbonsaure aus Cevin und Germin von L. C. Craig & W. A. Jacobs erhalten worden war.