Journal ArticleDOI
Über die absolute Konfiguration des Morphins und verwandter Alkaloide
TLDR
Thebaine (VII) has been degraded to (−)-cis-[2-methyl-2-carboxy-cyclohexyl-(1)]-acetic acid (III), thus providing experimental proof of the absolute configuration of morphine, thebaine and related alkaloids as discussed by the authors.Abstract:
Thebaine (VII) has been degraded to (−)-cis-[2-methyl-2-carboxy-cyclohexyl-(1)]-acetic acid (III), thus providing experimental proof of the absolute configuration of morphine, thebaine and related alkaloids.read more
Citations
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Journal ArticleDOI
Two-dimensional separations and behaviour of alkaloids of various polarities on unmodified silica gel in polar and very polar neutral or acidic mobile phases
R. L. Munier,S. Meunier +1 more
TL;DR: In this article, two-dimensional thin-layer chromatography on unmodified silica gel under mild conditions is used for the separation of alkaloids of similar polarity and structure.
Book ChapterDOI
Basic mechanisms of drug action.
TL;DR: It is the aim of this review to discuss some of the recent attempts to reveal the basic mechanisms of drug action.
Book ChapterDOI
The Chemistry and Pharmacology of Morphinan Alkaloids
TL;DR: The chemistry of morphinan drugs is closely related to that of morphine through recognition of its structure by Robinson and Sugasawa (1933) and Schopf and Thierfelder (1939) as discussed by the authors.
Journal ArticleDOI
Structure and reactions of photothebainehydroquinone
TL;DR: The structure of photothebainehydroquinone was shown by X-ray crystallography to be 3a, which arises from 2 through a di-π-methane to vinylcyclopropane rearrangement as mentioned in this paper.
References
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Journal ArticleDOI
Untersuchungen über asymmetrische Synthesen III. Über die Anwendung der asymmetrischen Synthese zur Konfigurationsbestimmung bei Triterpenen und Steroiden
TL;DR: In this article, the erwahnten Triterpene and Steroide mit 30 Kohlenstoffatomen die gleiche Konfiguration und Konstellation im Ringe A besitzen, wie die Abkommlinge des Cholestanols-(3β), dessen absolute Konfigureuration mit Hilfe der asymmetrischen Synthese indirekt bestimmt wurde.
Journal ArticleDOI
A direct stereochemical correlation of a sesquiterpene alcohol with the steroids
Journal ArticleDOI