Journal ArticleDOI
Use of Anticholinergic Drugs and Cholinesterase Inhibitors and Their Association with Psychological Well-Being Among Frail Older Adults in Residential Care Facilities
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TLDR
Concomitant use of anticholinergic drugs and ChEIs is common among older adults and is associated with poor psychological well-being, according to a cross-sectional study conducted in Helsinki and Espoo, Finland.Abstract:
BackgroundDrugs with anticholinergic properties have harmful effects among frail older people and they may antagonize the effects of cholinesterase inhibitors (ChEIs) However, their association with psychological well-being has not been studiedObjective:To determine (1) the prevalence of the use of anticholinergic drugs, ChEIs, or their combination among older adults in residential care facilities and their association with psychological well-being, and (2) the association of anticholinergic drugs with an individual's psychological well-beingMethods:In 2007, all older adults (N = 1475) living in residential care facilities in the cities of Helsinki and Espoo, Finland, were assessed in a cross-sectional study A trained nurse retrieved data on demographic factors, regularly administered medications, and diagnoses from medical charts Psychological well-being was assessed using 6 questions concerning life satisfaction, zest for life, plans for the future, feeling needed, and feeling depressed or lonely, read more
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Journal ArticleDOI
Education to Reduce Potentially Harmful Medication Use Among Residents of Assisted Living Facilities: A Randomized Controlled Trial
Kaisu H. Pitkälä,Anna-Liisa Juola,Hannu Kautiainen,Helena Soini,U. Harriet Finne-Soveri,J. Simon Bell,Mikko P. Björkman,Mikko P. Björkman +7 more
TL;DR: Activating learning methods directed at nurses in charge of comprehensive care can reduce the use of harmful medications, maintain HRQoL, and reduce hospitalization in residents of assisted living facilities.
Journal ArticleDOI
Anticholinergic Drug Burden Tools/Scales and Adverse Outcomes in Different Clinical Settings: A Systematic Review of Reviews
Tomas J. Welsh,Tomas J. Welsh,Veronika van der Wardt,Grace Ojo,Adam L. Gordon,Adam L. Gordon,John R.F. Gladman +6 more
TL;DR: It was showed that the concept of anticholinergic burden has been variably defined and inconsistently described using a number of indices with different content and scoring, which varies between scores and has not been conclusively established.
Journal ArticleDOI
Anticholinergic Drugs in Geriatric Psychopharmacology.
TL;DR: Practical recommendations for the safe use of anticholinergics in clinical conditions affecting elderly patients, such as dementia, schizophrenia and acute hallucinatory episodes, depression, anxiety, Parkinson’s disease, cardiovascular conditions and urinary incontinence are suggested.
Journal ArticleDOI
Different methods, different results--how do available methods link a patient's anticholinergic load with adverse outcomes?
TL;DR: Differences in the development and evaluation of available methods calculating the anticholinergic load are described, finding that due to hugely varying tests for assessing outcomes, the methods are scarcely comparable.
Journal ArticleDOI
Quality of anticholinergic burden scales and their impact on clinical outcomes: a systematic review
Angela Lisibach,Valérie Benelli,Marco Giacomo Ceppi,Karin Waldner-Knogler,Chantal Csajka,Monika Lutters +5 more
TL;DR: There is need for good quality validation studies comparing multiple scales to define the best scale and to conduct a meta-analysis for the assessment of their clinical impact.
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