Journal ArticleDOI
Using the National Cancer Database for Outcomes Research: A Review.
Daniel J. Boffa,Joshua E. Rosen,Katherine Mallin,Ashley Loomis,Bryan E. Palis,Kathleen K. Thoburn,Donna M. Gress,Daniel P. McKellar,Lawrence N. Shulman,Lawrence N. Shulman,Matthew A. Facktor,David P. Winchester +11 more
TLDR
The National Cancer Database offers a critically important perspective on cancer care in the United States and investigators and their audiences should familiarize themselves with the advantages and shortcomings of the NCDB as well as its evolution over time.Abstract:
Importance The National Cancer Database (NCDB), a joint quality improvement initiative of the American College of Surgeons Commission on Cancer and the American Cancer Society, has created a shared research file that has changed the study of cancer care in the United States. A thorough understanding of the nuances, strengths, and limitations of the database by both readers and investigators is of critical importance. This review describes the use of the NCDB to study cancer care, with a focus on the advantages of using the database and important considerations that affect the interpretation of NCDB studies. Observations The NCDB is one of the largest cancer registries in the world and has rapidly become one of the most commonly used data resources to study the care of cancer in the United States. The NCDB paints a comprehensive picture of cancer care, including a number of less commonly available details that enable subtle nuances of treatment to be studied. On the other hand, several potentially important patient and treatment attributes are not collected in the NCDB, which may affect the extent to which comparisons can be adjusted. Finally, the NCDB has undergone several significant changes during the past decade that may affect its completeness and the types of available data. Conclusions and Relevance The NCDB offers a critically important perspective on cancer care in the United States. To capitalize on its strengths and adjust for its limitations, investigators and their audiences should familiarize themselves with the advantages and shortcomings of the NCDB, as well as its evolution over time.read more
Citations
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Journal ArticleDOI
Survival after Minimally Invasive Radical Hysterectomy for Early-Stage Cervical Cancer
Alexander Melamed,Daniel J. Margul,Ling Chen,Ling Chen,Nancy L. Keating,Marcela G. del Carmen,Junhua Yang,Brandon Luke L. Seagle,A.L. Alexander,Emma L. Barber,Laurel W. Rice,Jason D. Wright,Jason D. Wright,Masha Kocherginsky,Shohreh Shahabi,J. Alejandro Rauh-Hain +15 more
TL;DR: In an epidemiologic study, minimally invasive radical hysterectomy was associated with shorter overall survival than open surgery among women with stage IA2 or IB1 cervical carcinoma.
Journal ArticleDOI
Practical Guide to Surgical Data Sets: National Cancer Database (NCDB).
TL;DR: An overview of unique data elements in the NCDB is presented to provide an analytic framework when using the data set for the purposes of research and to ensure that appropriate methods are used during data analysis and reporting.
Journal ArticleDOI
Comparison of Population-Based Observational Studies With Randomized Trials in Oncology
Payal D. Soni,Holly E. Hartman,Robert T. Dess,Ahmed E. Abugharib,Steven G. Allen,Felix Y. Feng,Anthony L. Zietman,Reshma Jagsi,Matthew J. Schipper,Daniel E. Spratt +9 more
TL;DR: It was unable to identify any modifiable factor present in population-based observational studies that improved agreement with randomized trials, and there was no agreement beyond what is expected by chance, regardless of reporting quality or statistical rigor of the observational study.
Journal ArticleDOI
Prognostic Performance of the 2018 International Federation of Gynecology and Obstetrics Cervical Cancer Staging Guidelines.
Jason D. Wright,Koji Matsuo,Yongmei Huang,Ana I. Tergas,June Y. Hou,Fady Khoury-Collado,Caryn M. St. Clair,Cande V. Ananth,Alfred I. Neugut,Dawn L. Hershman +9 more
TL;DR: The FIGO 2018 staging schema provides improved discriminatory ability for women with stage IB tumors; however, classification of all women with positive lymph nodes into a single stage results in a very heterogeneous group of patients with highly variable survival rates.
Journal ArticleDOI
Association of Human Papillomavirus Status at Head and Neck Carcinoma Subsites With Overall Survival.
Hong Li,Sina J. Torabi,Wendell G. Yarbrough,Saral Mehra,Saral Mehra,Heather A. Osborn,Heather A. Osborn,Benjamin L. Judson,Benjamin L. Judson +8 more
TL;DR: Human papillomavirus positivity was associated with improved survival in 4 subsites (oropharynx, hypopharynX, oral cavity, and larynx), and the largest survival difference was noted in the oropharynx and hypopharyx subsites.
References
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Journal ArticleDOI
The National Cancer Data Base: A Powerful Initiative to Improve Cancer Care in the United States
TL;DR: The National Cancer Data Base (NCDB) is a nationwide oncology outcomes database that currently collects information on approximately 70% of all new invasive cancer diagnoses in the United States each year and serves as a powerful clinical surveillance and quality improvement mechanism for cancer programs participating in the ACoS Commission on Cancer (CoC) approvals program.
Journal ArticleDOI
Time to Surgery and Breast Cancer Survival in the United States.
Richard J. Bleicher,Karen Ruth,Elin R. Sigurdson,J. Robert Beck,Eric A. Ross,Yu-Ning Wong,Sameer A. Patel,Marcia Boraas,Eric I. Chang,Neal S. Topham,Brian L. Egleston +10 more
TL;DR: Overall and disease-specific survival as a function of time between diagnosis and surgery, after adjusting for patient, demographic, and tumor-related factors, is found to be lower.
Journal ArticleDOI
Comparison of Commission on Cancer-Approved and -Nonapproved Hospitals in the United States: Implications for Studies That Use the National Cancer Data Base
TL;DR: Compared with non-CoC-approved hospitals, CoC- approved hospitals were larger, were more frequently located in urban locations, and had more cancer-related services available to patients.
Journal ArticleDOI
Comparison of Cases Captured in the National Cancer Data Base with Those in Population-based Central Cancer Registries
TL;DR: Findings illustrate the strengths and limitations of NCDB as a resource for nationwide data on cancer diagnosis, treatment, and survival and highlight the geographic- and site-specific variation in N CDB case coverage.
Journal ArticleDOI
Disparities in Ovarian Cancer Care Quality and Survival According to Race and Socioeconomic Status
Robert E. Bristow,Matthew A. Powell,Noor Al-Hammadi,Ling Chen,J. Philip Miller,Phillip Y. Roland,Phillip Y. Roland,David G. Mutch,William A. Cliby +8 more
TL;DR: These data highlight statistically and clinically significant disparities in the quality of ovarian cancer care and overall survival, independent of NCCN guidelines, along racial and SES parameters.