Are all coronaviruses RNA viruses?
Answers from top 10 papers
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| Papers (10) | Insight |
|---|---|
| The coronaviruses contains the largest RNA genome among all other known RNA viruses, therefore the disease etiology can be understood by analyzing the genome sequence of SARS-CoV-2. | |
55 Citations | Our findings have direct applicability to the investigation of potentially all RNA viruses. |
| Since the coronaviruses exhibit extraordinary large RNA genome, also the rate of homologous recombination is high, which in turn contributes to the genetic diversity and interspecies host-switches of CoVs. | |
159 Citations | In this sense, then, coronaviruses behave in part like RNA viruses with segmented genomes. |
| Because coronavirus contains the longest viral RNA genome by far (and is probably one of the longest stable RNAs in nature), this approach seems to pave the way for the reverse genetics studies for all RNA viruses. | |
32 Citations | Thus, coronaviruses are promising virus vectors for vaccine development and, possibly, for gene therapy. |
292 Citations | It implies that, despite the general similarity to other positive strand RNA viruses, and particularly to potyviruses, coronaviruses possess a number of unique structural and functional features. |
| We show that coronaviruses that regularly infect tissues with abundant AVPs have CpG-deficient and U-rich genomes; whereas viruses that do not infect tissues with abundant AVPs do not share these sequence hallmarks. | |
| Like many other RNA viruses, coronavirus may subvert these cellular proteins from cellular RNA processing or translation machineries to play a role in viral replication. | |
Open access•Journal Article 48 Citations | Coronavirus RNA transcription and replication may serve as a paradigm of RNA synthesis for RNA viruses in general. |
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Coronaviruses are RNA viruses that infect humans and animals ?5 answersCoronaviruses (CoVs) are enveloped, plus-strand RNA viruses with the largest RNA genomes, infecting birds and mammals, causing various diseases in both humans and animals. Human coronaviruses (HCoVs) were first identified in the mid-1960s, causing enteric or respiratory infections, with recent emergences like SARS-CoV-2 leading to the ongoing pandemic. CoVs are classified into different genera based on their hosts, with Alphacoronaviruses and Betacoronaviruses originating mainly from bats, while Gammacoronaviruses and Deltacoronaviruses are sourced from birds. These viruses can cause a range of illnesses in animals, from gastrointestinal infections to respiratory diseases, with some strains being highly pathogenic and leading to outbreaks with high mortality rates in humans.
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