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Open accessJournal ArticleDOI
Garry Laverty, Brendan Gilmore 
27 Feb 2014
24 Citations
Alternatively the compound may invoke genetically programmed cell death, called apoptosis, where cells stop actively dividing and therefore growing [10].
Apoptosis is a closed box and it might make it possible to stop the many disease processes or accelerate the healing.
The induction of apoptosis or progression through the process of apoptosis can be inhibited by a group of protein called inhibitors of apoptosis.
The results suggest that this modified DNase1 can efficiently eliminate apoptosis-resistant cancer cells through apoptosis.
These observations indicate that ciprofloxacin applied at concentrations insufficient for induction of apoptosis may stop cell proliferation by inhibition of mitosis.
However, this coincides with activation of physiologic regulatory mechanisms, as increased IL-8, TNF-α, LPO, and NO, which try to stop tumor cells by inducing apoptosis.
Confirmation of apoptosis as a mechanism, and identification of how apoptosis is initiated to produce vitiligo, can serve as a basis for devising medications that might stop the progression of the disorder.
Journal ArticleDOI
Ellen E. Sheets, John Yeh 
01 Apr 1997-Annals of Medicine
39 Citations
Mutation of p53, found in approximately 50% of cancers, can stop the apoptotic process.
Too little apoptosis can promote cancer and autoimmune diseases; too much apoptosis can augment ischaemic conditions and drive neurodegeneration.
Book ChapterDOI
Manjari Dimri, Goberdhan P. Dimri 
01 Jan 2017
3 Citations
Vast majority of literature suggest that chemotherapeutics stop cancer progression by inducing apoptosis or cell death.