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Unrecognised genetic factors may determine the clinical spectrum of hereditary haemorrhagic telangiectasia including the hepatic manifestations.
Cirrhosis appears unlikely to be the cause of the above findings.
The results confirm the high frequency of cardiac abnormalities in patients with cirrhosis, regardless of cirrhosis etiology.
In patients with hereditary hemorrhagic telangiectasia and symptomatic liver-involvement, the typical clinical presentations include high-output heart failure, portal hypertension, and biliary disease.
This observation could be relevant to patients with cirrhosis.
These aspects help in differentiating this condition from cirrhosis.