Showing papers on "Sequence analysis published in 1973"
TL;DR: The DNA sequence corresponding to the gene G spike protein initiation site has been determined by analysis of endonuclease IV and ‘Streptodornase’ digests.
Abstract: The DNA sequence corresponding to the gene G spike protein initiation site has been determined by analysis of endonuclease IV and ‘Streptodornase’ digests. The sequence has many features in common with RNA phage initiation sites.
50 citations
TL;DR: A test is developed which computes the significance of each deletion/insertion hypothesized, based on Monte-Carlo sampling of random sequences with the same base composition as the experimental sequences being tested, which confirms the relation of Escherichia coli and KB carcinoma 5 S RNAs and establishes the previously undetected homology between Pseudomonas fluorescens and KB 5 SRNAs.
38 citations
TL;DR: This dodecanucleotide was found to bind to exonuclease III-treated λDNA and it can be used as a primer for the incorporation of deoxynucleotides to its 3′-end and two molecules of dAMP were incorporated to the end of this primer.
33 citations
TL;DR: Characterization of the labeled bands and of purified, unbanded mRNA preparations, by partial sequence analysis of the oligonucleotides obtained following T1 and pancreatic RNase digestion, revealed that the bands represented discrete segments of the trp mRNA molecule, suggesting that endonucleolytic cleavage occurs in vivo at specific sites in the mRNA molecule.
21 citations
TL;DR: From the characteristic mobilities of these oligonucleotides in two dimensional fractionation systems, the 3′ terminal sequence -ACCCGCG for the r-strand and -GGTTACG forThe l-Strand of λ DNA have been determined.
11 citations
01 Jan 1973
TL;DR: The results of molecular hybridization experiments havedemonstrated that theRNA genome of RD-114virus has extensive nucleotide sequence homology with the RNA genome ofCrandell virus, an endogenous typeC virus ofcats, but onlylimited homologywith the RNA genomes offeline sarcoma virus andfeline leukemia virus.
Abstract: Theresults ofmolecular hybridization experiments havedemonstrated that theRNA genome ofRD-114virus hasextensive nucleotide sequence homology withtheRNA genome ofCrandell virus, an endogenous typeC virus ofcats,but onlylimited homology withtheRNA genomes offeline sarcoma virus andfeline leukemia virus. Thegenomic RNAsofRD-114virus andCrandell virus alsohad identical sedimentation coefficients of50S.A structural rearrangementof genomic RNA didnotexist within released RD-114virions, whereas a structural rearrangement ofgenomic RNA didoccur within feline sarcoma virions and feline leukemia virions after release fromvirus-producing cells. A typeCvirus, designated RD-114, hasbeen isolated fromahumanrhabdomyosarcoma cell line(RD)after inoculation intofetal catsin utero (20). Present immunological evidence ap