Showing papers on "Total synthesis published in 1985"
183 citations
TL;DR: It is conclusively proved by this chemical synthesis that lipid A is the active principle of bacterial endotoxin.
175 citations
TL;DR: Synthese de la lipoxine A (acide trihydroxy-5,6,15 eicosatetraene-7,9,11,13oique) et de ses isomeres tout-trans
Abstract: Synthese de la lipoxine A (acide trihydroxy-5,6,15 eicosatetraene-7,9,11,13oique) et de ses isomeres tout-trans
144 citations
TL;DR: Synthese a partir de la methyl-6a tetrahydro cyclopenta [b] furannone-2, avec comme etape cle la cyclisation d'un iodoalkyl alcynyl cyclopentene intermediaire
Abstract: Synthese a partir de la methyl-6a tetrahydro cyclopenta [b] furannone-2, avec comme etape cle la cyclisation d'un iodoalkyl alcynyl cyclopentene intermediaire
139 citations
TL;DR: In this article, a ring-forming aminomecuration was used to synthesize potent glycosidase inhibitors based on a high-yield ring forming aminorecuration.
107 citations
TL;DR: In this article, a novel radical-initiated polyolefinic cyclization approach to linear condensed cyclopentanoids is reported, executed in three stages: (1) Sn2′-anti opening of a vinyl lactone, (2) rapid elaboration to a cyclization precursor, and (3) single step tandem radical cyclization to produce a cis-anticis tricyclo[3.3.0]undecane.
104 citations
97 citations
92 citations
92 citations
TL;DR: Synthese basee sur la condensation de Friedlander de l'amino-2 benzyloxy-3 bromo-4 benzaldehyde et d'acetyl-1 methyl-4 β-carbolinecarboxylate-3 de methyle prepare a partir de Pd(0) de l"acetyl6 amino-5 bromomino-4 phenyl-4 methyl-5 pyridinedicarboxylates-2,6 de dimethyle via la cyclisation en presence de complexe de P
Abstract: Synthese basee sur la condensation de Friedlander de l'amino-2 benzyloxy-3 bromo-4 benzaldehyde et d'acetyl-1 methyl-4 β-carbolinecarboxylate-3 de methyle prepare a partir d'amino-3 bromo-2' phenyl-4 methyl-5 pyridinedicarboxylate-2,6 de dimethyle via la cyclisation en presence de complexe de Pd(0) de l'acetyl-6 amino-5 bromo-2' phenyl-4 methyl-3 picolinate de methyle
88 citations
TL;DR: Le trimethylsilyl-1 phenylthio-1 ethylene reagit avec les chlorures dacyle cycliques α, β insatures pour donner des β-mercaptophenylcyclopentenones as mentioned in this paper.
Abstract: Le trimethylsilyl-1 phenylthio-1 ethylene reagit avec les chlorures d'acyle cycliques α, β insatures pour donner des β-mercaptophenylcyclopentenones. La reaction a ete appliquee a la synthese de l'hirsutene
TL;DR: Synthese de l'ovalicine a partir de l"hydroxymethyl-2 methoxy-5phenol et al. as mentioned in this paper and l'iodo-2methyl-6heptadiene-2,5
Abstract: Synthese de l'ovalicine a partir de l'hydroxymethyl-2 methoxy-5phenol et de l'iodo-2methyl-6heptadiene-2,5
TL;DR: The total synthesis of Δ9(12)-capnellene is reported in this paper, where the key reaction involves construction of two rings in a single step via a tandem radical cyclization.
TL;DR: Synthese en 21 etapes a partir d'acetoxy-6 methyl-4 hexene-4al et de methoxy-3 cyclohexene-2one
Abstract: Synthese en 21 etapes a partir d'acetoxy-6 methyl-4 hexene-4al et de methoxy-3 cyclohexene-2one
TL;DR: Synthese a partir de la cetone de Nieland-Miescher avec comme etape cle l'alkylation reductrice d'une benzo [e] indenone-1
Abstract: Synthese a partir de la cetone de Nieland-Miescher avec comme etape cle l'alkylation reductrice d'une benzo [e] indenone-1
TL;DR: In this article, the reaction de Wadsworth-Emmons entre le t-butyldimethylsiloxy-3 dimethoxyphosphoryl-6 oxo-5 caproate de methyle et l'hexahydro-1,2,6,7,8,8-8a methyl-2 methyl 2' butyryloxy-8 naphtalenecarbaldehyde-1.
Abstract: Synthese via la reaction de Wadsworth-Emmons entre le t-butyldimethylsiloxy-3 dimethoxyphosphoryl-6 oxo-5 caproate de methyle et l'hexahydro-1,2,6,7,8,8a methyl-2 methyl-2' butyryloxy-8 naphtalenecarbaldehyde-1. Application a la synthese d'analogues
TL;DR: Synthese a partir d'une cycloaddition entre le phenylseleno-2 propanal and le benzoyloxy-1 [furyl-2]-4 methoxy-4 trimethylsiloxy-2 butadiene-1,3 as mentioned in this paper.
Abstract: Synthese a partir d'une cycloaddition entre le phenylseleno-2 propanal et le benzoyloxy-1 [furyl-2]-4 methoxy-4 trimethylsiloxy-2 butadiene-1,3
TL;DR: In this paper, a partir de l'acide dichloro-6,6 methyl-3oxo-7bicyclo [3.2] heptanecarboxylique-3
Abstract: Synthese en 18 etapes a partir de l'acide dichloro-6,6 methyl-3oxo-7bicyclo [3.2.0] heptanecarboxylique-3
TL;DR: Aldol condensation between O -benzyl D-or L-lactaldehyde and alkyl 3-nitropropionates in the presence of various catalysts leads to stereoisomeric nitroaldol products which can be transformed into aminodeoxy hexoses in the D- or L-series as mentioned in this paper.
TL;DR: In this paper, a three-step total synthesis of (±)-silphinene is described, which illustrates the high process selectivity attainable with the arene-olefin metaphotocycloaddition and a method for selective transformation of metacycloadducts.
TL;DR: Valeraldehyd (I) wird durch zweimalige Wittig-Reaktion in das Dien (IIIa) ubergefuhrt; die intramolekulare cycloaddition des davon abgeleiteten Nitrosoderivates (IIIc) ergibt den Bicyclus (IV).
Abstract: Valeraldehyd (I) wird durch zweimalige Wittig-Reaktion in das Dien (IIIa) ubergefuhrt; die intramolekulare Cycloaddition des davon abgeleiteten Nitrosoderivates (IIIc) ergibt den Bicyclus (IV).