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A. Toby A. Jenkins
Researcher at University of Bath
Publications - 92
Citations - 3049
A. Toby A. Jenkins is an academic researcher from University of Bath. The author has contributed to research in topics: Chemistry & Boronic acid. The author has an hindex of 29, co-authored 81 publications receiving 2530 citations. Previous affiliations of A. Toby A. Jenkins include University of Leeds & University of Sheffield.
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Journal ArticleDOI
Exploiting the Reversible Covalent Bonding of Boronic Acids: Recognition, Sensing, and Assembly
Steven D. Bull,Matthew G. Davidson,Jean M. H. van den Elsen,John S. Fossey,A. Toby A. Jenkins,Yun-Bao Jiang,Yuji Kubo,Frank Marken,Kazuo Sakurai,Jianzhang Zhao,Tony D. James +10 more
TL;DR: The dynamic covalent functionality of boronic acids with structure-directing potential has led researchers to develop a variety of self-organizing systems including macrocycles, cages, capsules, and polymers.
Journal ArticleDOI
S. aureus IgG-binding proteins SpA and Sbi: host specificity and mechanisms of immune complex formation.
Karen Atkins,Julia Burman,Emily S. Chamberlain,Jessica E. Cooper,Bernard Poutrel,Stefan Bagby,A. Toby A. Jenkins,Edward J. Feil,Jean M. H. van den Elsen +8 more
TL;DR: Homology models of immunoglobulin-binding domains of SpA and Sbi in complex with Fc reveal the molecular basis of the Fab-independent formation of insoluble complexes by Sbi, and notes remarkable sequence conservation within the IgG- binding domains of these genes, consistent with a lack of host specificity.
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An ESIPT Probe for the Ratiometric Imaging of Peroxynitrite Facilitated by Binding to Aβ-Aggregates.
Adam C. Sedgwick,Adam C. Sedgwick,Wei Tao Dou,Jin Biao Jiao,Luling Wu,George T. Williams,A. Toby A. Jenkins,Steven D. Bull,Jonathan L. Sessler,Xiao-Peng He,Tony D. James,Tony D. James +11 more
TL;DR: The 3-HF-OMe probe was found to produce a ratiometric response toward ONOO- when bound to Aβ aggregates, resulting in a novel host-guest ensemble, which adds insight into the development of other ESIPT-based probes for the simultaneous sensing of fibrous proteins/peptides and environmental ROS/RNS.
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A thin film detection/response system for pathogenic bacteria
TL;DR: Preliminary approaches to achieving responsive dressings which release antimicrobials and change color only on infected wounds are detailed, including vesicle-bacteria studies in aqueous suspension, and fluorescence imaging of fluorescein containing vesicles lysed by S. aureus and P. aeruginosa, but not by E. coli.
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Prototype Development of the Intelligent Hydrogel Wound Dressing and Its Efficacy in the Detection of Model Pathogenic Wound Biofilms
Naing Tun Thet,Diana R. Alves,Diana R. Alves,J. E. Bean,Simon Booth,Simon Booth,Jonathan Nzakizwanayo,Amber Young,Brian V. Jones,Brian V. Jones,A. Toby A. Jenkins +10 more
TL;DR: A prototype wound dressing is reported, which switches on a fluorescent color when in contact with pathogenic wound biofilms, suggesting that the level of expression of virulence factors is different depending of the growth mode.